摘要
目的:探讨采用红外热成像精准电参数刺激治疗早发型卵巢功能不全的临床效果。方法:选取100例早发性卵巢功能不全患者作为研究对象,按照不同治疗方法分为对照组与研究组,每组各50例。对照组采用雌孕激素进行治疗;研究组采用红外热成像精准电参数刺激治疗。比较治疗前及治疗后1、2、3个月两组患者血清激素[促卵泡生成素(FSH)、促黄体生成素(LH)、雌二醇(E2)及抗苗勒氏管激素(AMH)]水平、血流情况[卵巢血管收缩期峰值血流速度(PSV)、计算搏动指数(PI)及阻力指数(RI)]、基础窦卵泡数及卵巢体积,并比较两组患者不良反应发生情况及临床疗效。结果:治疗1、2、3个月后,两组患者FSH及LH水平均下降,且研究组低于对照组;E2及AMH水平均升高,且研究组高于对照组(P<0.05)。治疗3个月后,两组患者PSV水平均升高,PI水平均降低,且研究组RI水平低于治疗前(P<0.05)。治疗2、3个月后,两组患者基础窦卵泡数及两侧卵巢体积水平均呈上升趋势;治疗3个月后,研究组基础窦卵泡数及两侧卵巢体积水平均高于对照组(P<0.05),治疗有效率高于对照组(P<0.05),不良反应发生率低于对照组(P<0.05)。结论:采用红外热成像精准电参数刺激治疗早发性卵巢功能不全的患者安全性较高,利于改善患者性激素水平,并可增加基础窦卵泡数及增大卵巢体积,具有较好的临床疗效,可以在基层医院临床推广应用。
Objective:To investigate the clinical efficacy of using infrared thermography for precise electro-parametric stimulation in the treatment of early onset ovarian insufficiency.Methods:100 patients with premature ovarian insufficiency were selected as the subjects and were divided into a control group and a study group according to different treatment methods,with 50 cases in each group.The control group was treated with estrogen and progesterone,and the study group was treated with infrared thermography precise electrical parameter stimulation.The serum hormone levels[follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol(E2)and anti-mullerian hormone(AMH)],blood flow[peak systolic flow velocity(PSV),calculated pulsatility index(PI),and resistance index(RI)],the basal sinus follicle number,and the ovarian volume at pre-treatment,1,2 and 3 months after treatment,the adverse reactions and the clinical outcomes were compared between the two groups.Results:After 1,2 and 3 months of treatment,the levels of FSH and LH in both groups of patients decreased,the levels of E2 and AMH increased,and FSH and LH levels in the study group were lower than those in the control group,E2 and AMH levels were higher than those in the control group(P<0.05).After 3 months of treatment,PSV level in both groups was higher than before treatment,PI level was lower than before treatment,RI level in the study group was lower than before treatment(P<0.05).After 1,2 and 3 months of treatment,the number of basal sinus follicles and bilateral ovarian volume levels in both groups showed an increasing trend,and after 3 months of treatment,the number of basal sinus follicles and bilateral ovarian volume levels in the study group were higher than those in the control group(P<0.05).The incidence of adverse reactions was lower in the study group than in the control group(P<0.05).The treatment efficiency of the study group was higher than that of the control group(P<0.05).Conclusion:The treatment of early-onset ovarian insufficiency with infrared thermography precise electrical parameter stimulation is safer,favors the improvement of the patient s sex hormone level,and can increase the number of basal sinus follicles and enlarge the ovarian volume,which has better clinical efficacy,and is suitable for the clinical promotion of the application in the grassroots hospitals.
作者
唐玉云
黄金花
阮玉玲
徐秋
TANG Yu-yun;HUANG Jin-hua;RUAN Yu-ling;XU Qiu(Department of Obstetrics and Gynecology,the First People s Hospital of Qinzhou,Qinzhou 535099,Guangxi,China)
出处
《川北医学院学报》
CAS
2024年第6期783-786,794,共5页
Journal of North Sichuan Medical College
基金
广西壮族自治区卫生健康委员会自筹经费科研项目(Z-N20221868)。
关键词
红外热成像
早发性卵巢功能不全
血清激素
临床疗效
Infrared thermography
Early onset ovarian insufficiency
Serum hormones
Clinical efficacy
