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基于循证理论的全程干预在肝癌经导管动脉栓塞化疗患者中的应用效果

Application effect of whole-course intervention based on evidence-based theory in patients with liver cancer undergoing transcatheter arterial chemoembolization
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摘要 目的目的探讨基于循证理论的全程干预在肝癌经导管动脉栓塞化疗(TACE)患者中的应用效果。方法方法根据干预方式的不同将185例行TACE治疗的肝癌患者分为对照组(n=92,常规干预)和观察组(n=93,基于循证理论的全程干预)。比较两组患者的心理状态[焦虑自评量表(SAS)和抑郁自评量表(SDS)]、疼痛程度[数字分级评分法(NRS)]、生活质量[生活质量量表(QOL)]及并发症发生情况。结果结果干预后,两组患者SAS、SDS评分均低于本组干预前,观察组患者SAS、SDS评分均低于对照组,差异均有统计学意义(P﹤0.05)。术后2、4、8 h,两组患者NRS评分均低于本组术前,观察组患者NRS评分均低于对照组,差异均有统计学意义(P﹤0.05)。干预后,两组患者QOL评分均高于本组干预前,观察组患者QOL评分高于对照组,差异均有统计学意义(P﹤0.05)。观察组患者的并发症总发生率低于对照组(P﹤0.05)。结论结论基于循证理论的全程干预应用于肝癌TACE治疗患者,可减轻疼痛程度,改善心理状态,提高生活质量,降低并发症发生率。 Objective To explore the application effect of whole-course intervention based on evidence-based theory in patients with liver cancer undergoing transcatheter arterial chemoembolization(TACE).Method A total of 185 liver cancer patients who received TACE treatment were divided into control group(n=92,conventional intervention)and ob-servation group(n=93,whole-course intervention based on evidence-based theory)according to different intervention methods.The psychological status[self-rating anxiety scale(SAS)and self-rating depression scale(SDS)],pain degree[numerical rating scale(NRS)],quality of life[quality of life scale(QOL)]and complications were compared between the two groups.Result After intervention,the SAS and SDS scores in the two groups were lower than those before interven-tion,and the SAS and SDS scores in observation group were lower than those in control group,and the differences were statistically significant(P<0.05).At 2,4 and 8 h after surgery,the NRS scores in the two groups were lower than those be-fore surgery,and the NRS scores in observation group were lower than those in control group,and the differences were statistically significant(P<0.05).After intervention,the QOL scores in the two groups were higher than those before inter-vention,and the QOL score in observation group was higher than that in control group,and the differences were statisti-cally significant(P<0.05).The total incidence of complications in observation group was lower than that in control group(P<0.05).Conclusion Whole-course intervention based on evidence-based theory can reduce pain degree,improve psy-chological state and quality of life,reduce complications in liver cancer patients undergoing TACE.
作者 窦晓雅 卢瑞杰 苏冰 杨凯 门翔 DOU Xiaoya;LU Ruijie;SU Bing;YANG Kai;MEN Xiang(Department of Infection,Nanyang Central Hospital,Nanyang 473000,He’nan,China;Department of Respiratory Medicine,Nanyang Central Hospital,Nanyang 473000,He’nan,China)
出处 《癌症进展》 2024年第9期1011-1014,共4页 Oncology Progress
基金 河南省2022年科技发展计划项目(222102310528)。
关键词 循证理论 全程干预 肝癌 经导管动脉栓塞化疗 应用效果 evidence-based theory whole-course intervention liver cancer transcatheter arterial chemoemboliza-tion application effect
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