摘要
代谢相关脂肪性肝病(Metabolic Associated Fatty Liver Disease, MAFLD)与2型糖尿病(Type 2 Diabetes Mellitus, T2DM)的发病率在全球范围内呈现高流行的趋势,超过70%的T2DM患者可能罹患MAFLD,而MAFLD患者患糖尿病的风险比普通人高出约5倍,二者严重威胁人类健康.当MAFLD合并T2DM时,T2DM病情更难控制,MAFLD也更容易恶化,患者罹患心血管疾病、恶性肿瘤的几率更高,死亡风险更大.本文主要对MAFLD合并T2DM的流行病学、发病机制、危险因素及治疗方法进行系统阐述,旨在提升对MAFLD合并T2DM的认识,以更好地指导临床诊治.
Metabolic Associated Fatty Liver Disease(MAFLD)and Type 2 Diabetes Mellitus(T2DM)are highly prevalent worldwide.More than 70%of patients with T2DM may develop MAFLD,and patients with MAFLD have a risk of diabetes that is about 5 times higher than the general population,both of which are serious threats to human health.When MAFLD is combined with T2DM,it is more difficult to control T2DM,MAFLD is more likely to deteriorate,and patients have a higher incidence of cardiovascular disease,malignant tumors,and a greater risk of death.In this study,the epidemiology,pathogenesis,risk factors and treatment methods of MAFLD complicated with T2DM are systematically described,aiming to improve the understanding of MAFLD complicated with T2DM and provide better guidance for clinical diagnosis and treatment.
作者
李园
向平
李学锋
彭霞
LI Yuan;XIANG Ping;LI Xuefeng;PENG Xia(School of Medicine,Jishou University,Jishou 416000,Hunan China;Xiangxi Tujia and Miao Autonomous Prefecture People's Hospital,Jishou 416000,Hunan China)
出处
《吉首大学学报（自然科学版）》
CAS
2024年第3期91-96,共6页
Journal of Jishou University(Natural Sciences Edition)
关键词
代谢相关脂肪性肝病
2型糖尿病
胰岛素抵抗
metabolism-related fatty liver disease
type 2 diabetes
insulin resistance
