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Research progress on natural products against hepatocellular carcinoma

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摘要 Hepatocellular carcinoma(HCC)remains a prevalent and challenging malignancy globally,characterized by its numerous causal factors and generally unfavorable prognosis.In the relentless pursuit of effective treatment modalities,natural products have emerged as a promising and relatively non-toxic alternative,garnering significant interest.The integration of natural products with contemporary medical research has yielded encouraging therapeutic outcomes in the management of HCC.This review offers a comprehensive overview of the causal factors underlying HCC,and the diverse treatment options available,and highlights the advancements made by natural products in anti-HCC research.Particularly,we provide an outline of the various types of natural products,their corresponding nomenclature,target molecules,and mechanisms of action that exhibit anti-HCC activities.Natural products are anticipated to play a pivotal role in future comprehensive treatment plans for liver cancer,potentially offering patients improved survival rates and an enhanced quality of life.
出处 《BIOCELL》 SCIE 2024年第6期905-922,共18页 生物细胞(英文)
基金 This work was supported by Chongqing Natural Science Foundation General Project(2023NSCQ-MSX1633,CSTB2023NSCQ-MSX0393) Key Scientific and Technological Research Project of Chongqing Municipal Education Commission(KJ202302884457913,KJZD-K202302801) 2022 Scientific Research Project of Chongqing Medical and Pharmaceutical College(ygz2022104) Scientific Research and Seedling Breeding Project of Chongqing Medical Biotechnology Association(cmba2022kyym-zkxmQ0003) Chongqing Natural Science Foundation(cstc2021jcyj-msxm3191,cstc2021jcyj-msxm0452),respectively.
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