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全身运动质量评估风险分级干预策略对低出生体重儿神经发育的影响

Follow-up study of neurodevelopment of low birth weight infants with varying risk grades by general movements assessments
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摘要 目的 研究全身运动质量评估(GMs)不同风险分级干预对低出生体重儿在纠正6、12个月龄神经发育的影响。方法 选取新生儿科住院接受全身运动质量评估的低出生体重儿150例,出院后在门诊复评GMs。150例早产儿按GMs 2个阶段的评估结果分为高风险Ⅰ级、中风险Ⅱ级、低风险Ⅲ级,制定不同早期干预策略,比较3组患儿纠正6、12个月龄神经发育结果及纠正12个月龄时神经发育结局。结果 纠正6个月龄3组患儿龄精细动作、社会适应、语言、个人社交行为4个领域发育商评分比较,差异均有统计学意义(P<0.05)。纠正12个月龄3组患儿在粗大运动、精细运动、社会适应、语言、个人社交行为5个领域商评分比较,差异有统计学意义(P<0.01)。纠正12个月龄,神经发育结局异常9例,其中脑性瘫痪1例(高风险Ⅰ级),运动发育迟缓8例(高风险Ⅰ级2例、中风险Ⅱ级4例、低风险Ⅲ级2例)。结论 应用GMs评估结果不同风险分级精细化管理指导。能够促进低出生体重儿神经发育,减少神经发育异常,可在临床工作中进一步推广和应用。 Objective To analyze the effect of early rehabilitation interventions based on the risk grades of general movements(GMs)assessment on the neurodevelopment of low birth weight infants with corrected age of 6 and 12 months,thus providing references for formulating clinical management and rehabilitation plans.Methods A total of 150 low birth weight infants who received GMs in the department of neonatology and re-examined in outpatient clinic after discharge.According to the two rounds of evaluation results,the premature babies were assigned into high-risk group(gradeⅠ),moderate-risk group(gradeⅡ)and low-risk group(gradeⅢ).They were managed by early rehabilitation interventions based on the risk grades of GMs.Neurodevelopmental results at the corrected age of 6 and 12 months,and neurodevelopmental outcome at the corrected age of 12 months were compared among the three groups.Results At the corrected age of 6 months,there were significant differences in developmental quotient scores of fine motor,social adaptation,language,and personal social behavior among the three groups(P<0.05).At the corrected age of 12 months,there were significant differences in the scores of five domains among the three groups(P<0.01).At the corrected age of 12 months,9 cases had abnormal neurodevelopmental outcome,including 1 case of cerebral palsy(high-risk gradeⅠ)and 8 cases of motor development delay(high-risk gradeⅠin 2 cases,moderate-risk gradeⅡin 4 cases,low-risk gradeⅢin 2 cases).Conclusion Fined management guidance based on GMs at varying risk grades can promote the neurological development of low birth weight infants and reduce neurodevelopmental abnormalities,which can be further promoted and applied in clinical work.
作者 杨丽红 李雪莉 种月先 尹中信 陈杰 孙梅 丁阳 YANG Lihong;LI Xueli;ZHONG Yuexian(Department of Pediatrics,Baoding Maternal and Child Health Hospital,Hebei,Baoding 071000,China;不详)
出处 《河北医药》 CAS 2024年第13期1965-1969,共5页 Hebei Medical Journal
基金 河北省保定市科技计划项目(编号:2141ZF284)。
关键词 全身运动评估 低出生体重儿 早期干预 神经发育 general movements low birth weight infant early intervention neurodevelopment
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