摘要
香菊制剂是香菊片、香菊滴剂和香菊胶囊的统称,是同一验方研制的剂型不同的中成药,具有清热解毒、辛散祛风的功效,是耳鼻喉科常用药物之一。本文在前期文献研究的基础上,利用文献归纳法,对近年来香菊制剂的化学成分、药理活性以及在鼻窦炎、中耳炎中的临床应用疗效和用药护理等进行系统综述,香菊制剂中已鉴定化学成分137种,主要为黄酮、苯丙素和有机酸等,其药理活性主要通过酚类、黄酮、生物碱和挥发油等化合物来发挥药效,进而表现出消炎、消肿和抗菌等功效;在临床应用方面,香菊制剂能联合多种治疗手段来提高鼻窦炎、中耳炎治疗的总有效率和显效率,具有安全性与有效性,且适当的用药护理干预可提高患者的治疗效果。本文系统阐述了香菊制剂在鼻窦炎和中耳炎治疗中的药效物质、药理活性及其临床使用情况,可为香菊制剂的临床应用推广提供科学依据。
Xiangju preparation is the general name of Xiangju tablets,Xiangju drops and Xiangju capsules.It is a Chinese patent medicine with different dosage forms developed by the same prescription,has the effect of clearing heat and detoxifying,dispelling wind,and is one of the commonly used drugs in ear,nose and thoat department.On the basis of previous literature studies,this paper systematically reviewed the chemical composition,pharmacological activity,clinical efficacy and medication nursing of Xiangju preparation in sinusitis and otitis media in recent years by literature induction method.There are 137 chemical components identified in the preparation,mainly flavonoids,phenyl-propanoids and organic acids,etc.Its pharmacological activity is mainly through phenols,flavonoids,alkaloids and volatile oils and other compounds to play efficacy,and then show anti-inflammatory,deswelling and antibacterial effects.In terms of clinical application,Xiangju preparation can be combined with a variety of therapeutic means to improve the total effective rate and significant efficiency of the treatment of sinusitis and otitis media,with safety and effectiveness,and appropriate medication nursing intervention can improve the therapeutic effect of patients.The pharmacodynamic substances,pharmacological activities and clinical application of Xiangju preparation in the treatment of sinusitis and otitis media were systematically described in this paper,which can provide scientific basis for the clinical application and promotion of Xiangju preparation.
作者
魏墚铉
郭艳平
王维
孔军
胡华林
WEI Liangxuan;GUO Yanping;WANG Wei;KONG Jun;HU Hualin(Department of Otolaryngology,Guiyang First People's Hospital,Guizhou Province,Guiyang550002,China;Department of Facial Features,Jiangkou County People's Hospital,Guizhou Province,Tongren554400,China;Natural Products Research Center of Guizhou Province,Guizhou Province,Guiyang550014,China)
出处
《中国当代医药》
CAS
2024年第18期195-198,共4页
China Modern Medicine
基金
贵州省林业科研项目(黔林科合〔2022〕06号)。
关键词
香菊胶囊
鼻窦炎
中耳炎
总有效率
Xiangju Capsule
Sinusitis
Otitis media
Total effective rate
