摘要
重症肺炎属常见肺部疾病,发病率较高,好发于老年群体。老年重症肺炎患者由于自身免疫力低下,多合并基础疾病,故易合并多重耐药菌感染,两种疾病合并加剧了治疗难度,将严重威胁患者的生命健康。多重耐药菌感染主要是由多种病原菌所致,其中以革兰阴性菌为主,且耐药性较强,这加大了临床治疗的难度,耐药机制复杂,了解病原菌的类型与分布情况能够提高重症肺炎患者合并多重耐药菌感染治愈机率。鉴于此,本文查阅国内外研究文献,旨在综述老年重症肺炎患者并发多重耐药菌感染的病原菌分布研究进展,期望为临床诊治提供参考依据。
Severe pneumonia is a common lung disease,with a high incidence rate,which is common in the elderly.Elderly patients with severe pneumonia are prone to be infected with multi-drug resistant bacteria because of their low immunity and many basic diseases.The combination of the two diseases intensifies the difficulty of treatment and will seriously threaten the life and health of patients.Multi-drug-resistant bacteria infection is mainly caused by a variety of pathogens,among which Gram-negative bacteria are the main ones with strong drug resistance,which increases the difficulty of clinical treatment and the drug resistance mechanism is complex.Knowing the types and distribution of pathogens can improve the cure rate of patients with severe pneumonia complicated with multi-drug-resistant bacteria infection.In view of this,this paper refers to the research literature at home and abroad,aiming at summarizing the research progress of pathogenic bacteria distribution in elderly patients with severe pneumonia complicated with multidrug resistant bacteria infection,hoping to provide reference for clinical diagnosis and treatment.
作者
李喆
张智博
丁莉莉
赵克明
LI Zhe;ZHANG Zhibo;DING Lili;ZHAO Keming(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,China;Respiratory and Critical Care Medicine Department,Affiliated Hospital of Liaoning University of Traditional Chinese Medicine)
出处
《中国病原生物学杂志》
CSCD
北大核心
2024年第7期863-866,共4页
Journal of Pathogen Biology
基金
国家中医药管理局科技项目(No.2023ZYLCYJ05-02)。
关键词
老年
重症肺炎
多重耐药菌
感染
病原菌分布
综述
old age
severe pneumonia
multi-drug resistant bacteria
infection
distribution of pathogenic bacteria
review
