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人工流产术后即时口服左炔诺孕酮炔雌醇(三相)片的临床分析

Clinical analysis of oral levonorgestrel and ethinylestradiol tablets(triphasic)immediately after induced abortion
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摘要 目的 探析人工流产术后即时口服左炔诺孕酮炔雌醇(三相)片的应用效果。方法 研究筛选样本选取采取人工流产术终止妊娠的76例患者,分组处理方式选用随机数字表法,将纳选对象均衡划分,对照组、观察组2个独立样本各38例。对照组手术结束后常规用药,用药期间加强健康宣传教育,予以性生活以及饮食指导,观察组基于上述措施在术后即时口服左炔诺孕酮炔雌醇(三相)片。比较两组性激素[促黄体生成素(LH)、促卵泡生成素(FSH)、雌二醇(E_(2))]水平、子宫内膜恢复指标及术后并发症发生率。结果 治疗后,两组患者LH、FSH、E_(2)水平均高于治疗前,且观察组患者LH(9.52±1.47)U/L、FSH(11.32±1.34)U/L、E_(2)(56.50±4.42)pg/ml高于对照组的(8.74±1.44)U/L、(9.71±1.37)U/L、(47.82±4.37)pg/ml(P<0.05)。观察组阴道出血时间(2.67±1.12)d、月经复潮时间(31.64±3.93)d短于对照组的(3.95±1.46)、(36.42±4.71)d,阴道出血量(54.46±5.39)ml少于对照组的(61.98±7.46)ml,子宫内膜厚度(6.61±1.36)mm大于对照组的(5.08±1.04)mm(P<0.05)。两组术后并发症发生率测定数值分别为5.26%、21.05%,观察组较低(P<0.05)。结论 人工流产术后即时口服左炔诺孕酮炔雌醇(三相)片具有较高安全性、可行性,对于促进月经恢复以及预防相关并发症具有显著效果,可提高患者生殖健康水平,值得推广应用。 Objective To explore the application effect of oral levonorgestrel and ethinylestradiol tablets(triphasic)immediately after induced abortion.Methods A total of 76 patients who underwent induced abortion to terminate pregnancy were selected for the study.Random number table method was used to divide the selected subjects into two independent samples of the control group and the observation group,each consisting of 38 cases.The control group received routine medication after surgery,and health education and guidance on sexual activity and diet were strengthened during medication.The observation group took levonorgestrel ethinyl estradiol(triplephase)tablets orally immediately after surgery based on the above measures.Comparison was made on sex hormones[luteinizing hormone(LH),follicle stimulating hormone(FSH),estradiol(E_(2))]levels,endometrial recovery indicators,and incidence of postoperative complications between the two groups.Result After treatment,the levels of LH,FSH,and E_(2) in both groups of patients were higher than those before treatment;the observation group had LH of(9.52±1.47)U/L,FSH of(11.32±1.34)U/L,and E_(2) of(56.50±4.42)pg/ml,which were higher than(8.74±1.44)U/L,(9.71±1.37)U/L,and(47.82±4.37)pg/ml in the control group(P<0.05).The observation group had a shorter vaginal bleeding time of(2.67±1.12)d and a shorter time of return of menstruation of(31.64±3.93)d compared to the control group's(3.95±1.46)and(36.42±4.71)d;the amount of vaginal bleeding was(54.46±5.39)ml,which was less than(61.98±7.46)ml in the control group;the thickness of the endometrium was(6.61±1.36)mm,which was greater than(5.08±1.04)mm in the control group(P<0.05).The incidence of postoperative complications was measured to be 5.26%and 21.05%,respectively,with a lower incidence in the observation group(P<0.05).Conclusion Oral levonorgestrel and ethinylestradiol tablets(triphasic)immediately after induced abortion has high safety and feasibility,and has significant effect on promoting menstrual resumption and preventing related complications,which can improve patients'reproductive health,and is worthy of popularization and application.
作者 王海燕 WANG Hai-yan(Family Planning Department,Weifang Maternal and Child Health Hospital,Weifang 261000,China)
出处 《中国实用医药》 2024年第13期115-117,共3页 China Practical Medicine
关键词 人工流产术 即时口服 左炔诺孕酮炔雌醇(三相)片 临床效果 Induced artificial abortion Immediate oral administration Levonorgestrel and ethinylestradiol tablets(triphasic) Clinical effect
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