摘要
目的探讨高频超声用于浅表淋巴结良恶性鉴别的临床价值。方法回顾性分析2022年2月至2024年1月佛山市中医院收治的64例浅表淋巴结患者的临床资料,所有患者均接受高频超声检查,依据病理组织活检结果将其分为良性组21例和恶性组43例,比较两组患者的高频超声图像特征,绘制受试者工作特征(ROC)曲线,并采用Kappa一致性检验分析高频超声对恶性浅表淋巴结的诊断价值。结果良性组与恶性组患者的高频超声图像特征比较差异均有统计学意义(P<0.05),其中恶性浅表淋巴结表现为类圆形/圆形,未发现淋巴门结构,内部可见微小的钙化灶/囊状回声,边界清晰度不佳,彩色多普勒血流显像(CDFI)呈现为周边/混合型;良性组患者超声检测的长径值、短径值、长径/短径比值、RI值分别为(2.84±0.29)cm、(1.20±0.16)cm、2.35±0.26、0.62±0.07,明显低于恶性组的(3.11±0.35)cm、(1.32±0.15)cm、2.50±0.27、0.85±0.09,动脉收缩期血流速度为(31.85±3.29)cm/s,明显快于恶性组的(26.99±2.76)cm/s,差异均有统计学意义(P<0.05),但两组患者的舒张末期血流速度比较差异无统计学意义(P>0.05);高频超声诊断恶性浅表淋巴结的敏感度、特异度、曲线下面积(AUC)、Kappa值分别为83.72%、85.71%、0.847(95%CI 0.739~0.955)、0.662。结论高频超声对浅表淋巴结良恶性具有一定的鉴别诊断价值,值得临床推广应用。
Objective To investigate the clinical value of high-frequency ultrasound in differentiating benign and malignant superficial lymph nodes.Methods The clinical data of 64 patients with superficial lymph nodes admitted to Foshan Hospital of Traditional Chinese Medicine from February 2022 to January 2024 were retrospectively analyzed.All patients received high-frequency ultrasound examination and were divided into benign group(21 cases)and malignant group(43 cases)according to pathological biopsy results.The high-frequency ultrasound image features of the two groups were compared.Receiver operating characteristic(ROC)curve was plotted,and Kappa consistency test was used to analyze the diagnostic value of high-frequency ultrasound in malignant superficial lymph nodes.Results There were statistically significant differences between the benign group and the malignant group in high-frequency ultrasound image features(P<0.05).The malignant superficial lymph nodes showed quasi-circular/circular shape and had no lymphatic portal structure,with small calcification foci/cystic echoes inside,poor boundary resolution,which were displayed as peripheral/mixed type by color Doppler flow imaging(CDFI).The length diameter value,short diameter value,length diameter/short diameter ratio,and RI value detected by ultrasound in benign group were(2.84±0.29)cm,(1.20±0.16)cm,2.35±0.26,and 0.62±0.07,respectively,significantly lower than(3.11±0.35)cm,(1.32±0.15)cm,2.50±0.27,and 0.85±0.09 of malignant group;the systolic blood flow velocity was(31.85±3.29)cm/s,significantly higher than(26.99±2.76)cm/s of malignant group;the differences were statistically significant(P<0.05).There was no statistically significant difference in end-diastolic blood flow velocity between the two groups(P>0.05).The sensitivity,specificity,area under the ROC curve(AUC),and Kappa value of high-frequency ultrasound for diagnosing malignant superficial lymph nodes were 83.72%,85.71%,0.847(95%CI 0.739-0.955),and 0.662,respectively.Conclusion High-frequency ultrasound has certain diagnostic value in distinguishing between benign and malignant superficial lymph nodes,which is worthy of clinical promotion and application.
作者
黄春燕
陈冬菲
杨颖华
HUANG Chun-yan;CHEN Dong-fei;YANG Ying-hua(Department of Ultrasound,Foshan Hospital of Traditional Chinese Medicine,Foshan 528000,Guangdong,CHINA)
出处
《海南医学》
CAS
2024年第14期2067-2070,共4页
Hainan Medical Journal
关键词
高频超声
浅表淋巴结
良恶性
鉴别
临床价值
High-frequency ultrasound
Superficial lymph nodes
Benign and malignant
Differentiating
Clinical value
