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钬激光剜除术与等离子电切术在治疗大体积良性前列腺增生的对比研究

Comparative study of holmium laser enucleation and plasma resection in the treatment of large volume benign prostatic hyperplasia
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摘要 目的:比较经尿道前列腺钬激光剜除术(HoLEP)和经尿道前列腺双极等离子电切术(TUPKP)在临床上治疗大体积良性前列腺增生的效果和安全性。方法:回顾性分析2020年1月至2021年12月本院泌尿外科收治的76例大体积良性前列腺增生患者的临床资料,根据手术方式不同分为HoLEP组(45例)和TUPKP组(31例)。比较两组患者的围手术期指标、术后效果及并发症情况,并加以综合分析。结果:在围手术期方面,与TUPKP组比较,HoLEP组前列腺切除组织较多、术后冲洗时间较短、留置导尿时间较短、术后住院时间较短(均P<0.05);在术后效果方面,HoLEP组术后6个月国际前列腺症状评分(IPSS)下降值、生活质量评分(QOL)及最大尿流率(Q max)均优于TUPKP组(均P<0.05);两组术后总并发症发生率比较,差异无统计学意义[17.78%(8/45)vs.29.03%(9/31),P>0.05]。结论:HoLEP与TUPKP均是治疗大体积良性前列腺增生的有效手段,但从综合疗效比较来看,HoLEP比TUPKP更有优势,值得在临床上应用。 Objective To compare the efficacy and safety of transurethral holmium laser enucleation of prostate(HoLEP)and transurethral bipolar plasma resection of prostate(TUPKP)in the treatment of large volume benign prostatic hyperplasia.Methods The clinical data of 76 patients with large volume benign prostatic hyperplasia in urology department of our hospital from January 2020 to December 2021 were reviewed.They were divided into two groups according to different surgical methods,45 cases in HoLEP group and 31 cases in TUPKP group.The perioperative indicators,postoperative effects and complications were compared and analyzed comprehensively.Results In the perioperative period,compared with TUPKP group,HoLEP group had more prostate resection tissue,shorter postoperative irrigation time,shorter indenture catheterization time and shorter postoperative hospitalization time(all P<0.05).In terms of postoperative effect,the HoLEP group was superior to the TUPKP group in terms of the reduction of the International Prostate Symptom Score(IPSS),the improvement of the quality of life score(QOL)and the improvement of the maximum urinary flow rate(Qmax)6 months after surgery,with a statistically significant difference(all P<0.05).There was no significant difference in total complications between the two groups(P>0.05).Conclusions Both HoLEP and TUPKP are effective methods for the treatment of large volume benign prostatic hyperplasia,but from a comprehensive comparison,HoLEP has more advantages than TUPKP and is worthy of clinical application.
作者 范欣欢 翁同辉 梁前俊 陈德钢 桑士仿 徐鹏程 Fan Xinhuan;Weng Tonghui;Liang Qianjun;Chen Degang;Sang Shifang;Xu Pengcheng(Department of Urology,the Affiliated Lu′an Hospital of Anhui Medical University,Lu′an 237005,China)
出处 《国际泌尿系统杂志》 2024年第4期601-605,共5页 International Journal of Urology and Nephrology
关键词 前列腺增生 前列腺切除术 钬激光 等离子电切术 Prostatic Hyperplasia Prostatectomy Holmium Laser Plasma Electrocision
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