摘要
Lymph node (LN) metastasis is a process in which cancer cells travel from primary tumors to LNs via the lymphatic system,then proliferate and spread within the LNs. In most cancers,LN metastasis is a major mode of cancer dissemination,and a critical indicator of cancer progression and worsening prognosis1. The occurrence of LN metastasis indicates that the tumor has invaded the lymphatic system.
基金
funded by the National Key Research and Development Program of China (Grant No. 2022YFA1305500)
the National Natural Science Foundation of China (Grant Nos. 32322023, 82173272, 81825016, and 82173230)
the Key Areas Research and Development Program of Guangdong (Grant Nos. 2022B1515120086 and 2022A1515140175)
the Science and Technology Program of Guangzhou,China (Grant No. 2023A04J2206)。