摘要
目的:探讨通窍平鼾方治疗肺脾气虚型小儿腺样体肥大疗效。方法:将102例腺样体肥大(肺脾气虚型)患儿随机分为观察组(n=51)和对照组(n=51),对照组接受常规西医治疗,观察组联合通窍平鼾方治疗。治疗1个月后,比较2组临床疗效、复发率、中医证候积分、腺样体体积积分、血清过敏原特异性IgE(sIgE)、炎症指标及生活质量(OSA-18评分)。结果:观察组治疗后各项中医证候积分、腺样体体积积分、sIgE指标、TNF-a、IL-6指标、OSA-18评分、复发率均低于对照组(P<0.05);IL-10指标、总有效率均高于对照组(P<0.05)。结论:通窍平鼾方能够降低腺样体肥大患儿血清sIgE水平,缩小腺样体体积,调节炎症指标水平,改善预后。
Objective:To investigate the efficacy of Tongjiao Pinghan formula in the treatment of adenoid hypertrophy in children with lung and spleen Qi deficiency type.Methods:One hundred and two children with adenoid hypertrophy(lung and spleen Qi deficiency type)were randomly divided into an observation group(n=51)and a control group(n=51).The control group received conventional Western medical treatment,and the observation group was treated with Tongqiao Pinghan formula.The clinical efficacy,recurrence rate,TCM symptom score,adenoid volume score,serum allergen-specific IgE(sIgE)level,inflammation index and quality of life(OSA-18 score)were compared between the two groups after 1 month of treatment.Results:The TCM symptom score,adenoid volume score,sIgE index,TNF-a,IL-6 index,OSA-18 score,and recurrence rate were lower and IL-10 index and total effective rate were higher in the observation group than the control group after treatment(P<0.05).Conclusion:Tongqiao Pinghan formula can reduce the serum sIgE level and the volume of adenoids in children with adenoid hypertrophy,regulate the level of inflammatory indicators,and improve the prognosis.
作者
唐汝宁
王婷婷
TANG Runing;WANG Tingting(Department of Pediatrics,Traditional Chinese Medicine Hospital of Zhumadian,Zhumadian 463000,China)
出处
《上海医药》
CAS
2024年第13期34-37,43,共5页
Shanghai Medical & Pharmaceutical Journal
关键词
小儿腺样体肥大
通窍平鼾方
肺脾气虚证
SIGE
炎症指标
pediatric adenoid hypertrophy
Tongqiao Pinghan formula
lung and spleen Qi deficiency syndrome
sIgE
inflammation indicator
