摘要
目的 观察揿针配合四黄散外敷治疗急性痛风性关节炎(acute gouty arthritis, AGA)的临床疗效。方法 将60例AGA患者随机分为治疗组和对照组,每组30例。治疗组采用揿针配合四黄散外敷治疗,对照组采用口服双氯芬酸钠缓释胶囊治疗。观察两组治疗前及治疗第4、7天时视觉模拟评分法(visual analog scale, VAS)评分及各项实验室指标[红细胞沉降(erythrocyte sedimentation rate, ESR)、血尿酸(blood uric acid, BUA)、超敏C反应蛋白(hypersensitive C-reactive protein, hs-CRP)]的变化情况,并比较两组临床疗效及不良反应发生率。结果 治疗组总有效率为96.7%,明显高于对照组的80.0%(P<0.05)。两组治疗第4、7天时VAS评分及各项实验室指标均较同组治疗前显著降低,差异均有统计学意义(P<0.05)。治疗组治疗第4天时ESR水平明显低于对照组,治疗第4、7天时VAS评分及各项实验室指标均明显低于对照组,差异均有统计学意义(P<0.05)。治疗组不良反应发生率为3.3%,对照组为10.0%,两组比较差异无统计学意义(P>0.05)。结论 揿针配合四黄散外敷治疗AGA疗效确切,可缓解疼痛,调节ESR、BUA及hs-CRP水平,且安全性较好。
Objective To observe the clinical effect of needle-embedding therapy combined with Sihuang powder in the treatment of acute gouty arthritis(AGA).Method A total of 60 patients with AGA were randomly divided into a treatment group and a control group,with 30 cases in each group.The treatment group was treated with needle-embedding therapy combined with external application of Sihuang powder,and the control group was treated with oral diclofenac sodium extended-release capsules.The changes of visual analog scale(VAS)scores,laboratory indexes[ery-throcyte sedimentation rate(ESR),blood uric acid(BUA),hypersensitive C-reactive protein(hs-CRP)]in the two groups were observed before treatment and on the 4th and 7th d of treatment.The clinical efficacy and the incidence of adverse reactions between the two groups.Result The total effective rate of the treatment group was 96.7%,which was significantly higher than that of the control group(80.0%)(P<0.05).The VAS score and all laboratory indexes were significantly lower in both groups on the 4th and 7th d of treatment than in the same group before treatment,and the differences were statistically significant(P<0.05).The ESR level of the treatment group was significantly lower than that of the control group on the 4th d of treatment,and the VAS score and all laboratory indexes were significantly lower than those of the control group on the 4th and 7th d of treatment,with statistically significant differences(P<0.05).The incidence rate of adverse reactions was 3.3%in the treatment group and 10.0%in the control group,and the difference between the two groups was not statistically significant(P>0.05).Conclusion The efficacy of needle-embedding therapy combined with external application of Sihuang powder is effective in the treatment of AGA,which can relieve pain,regulate ESR,BUA and hs-CRP levels,and has good safety.
作者
金巧丽
马晓芬
马欢欢
王芳
JIN Qiaoli;MA Xiaofen;MA Huanhuan;WANG Fang(Pan’an Hospital of Traditional Chinese Medicine,Zhejiang Province,Jinhua 322305,China)
出处
《上海针灸杂志》
CSCD
2024年第7期779-784,共6页
Shanghai Journal of Acupuncture and Moxibustion
基金
磐安县科技计划项目(磐社科202107)。
关键词
针刺疗法
揿针
皮肤针疗法
关节炎
痛风性
视觉模拟评分
超敏C反应蛋白
针药并用
Acupuncture therapy
Needle-embedding therapy
Dermal needle therapy
Arthritis,gout,Visual analogue scale
Hypersensitive C-reactive protein
Combination of acupuncture and medication
