摘要
目的探讨阴式病灶切除联合子宫壁修补术治疗剖宫产术后子宫瘢痕妊娠(CSP)的疗效。方法选取我院收治的CSP患者122例,将其随机分为对照组(61例)和观察组(61例)。对照组患者给予子宫动脉化疗栓塞术(UACE)联合超声引导下清宫术治疗,观察组患者给予阴式病灶切除联合子宫壁修补术治疗。比较2组患者围术期指标,术前及术后3 d、5 d、7 d的血清β-人绒毛膜促性腺激素(β-hCG)水平,临床疗效,以及并发症发生情况。结果观察组患者手术时间较对照组明显更长(P<0.05),术中出血量、住院费用、阴道出血时间、月经恢复正常时间、瘢痕部位包块消失时间、β-hCG恢复正常时间、住院时间较对照组明显更少/短(P<0.05)。2组患者术后3 d、5 d、7 d血清β-hCG水平较术前均降低,且观察组低于对照组,差异均有统计学意义(P<0.05)。观察组治疗总有效率为96.72%,明显高于对照组的85.25%(P<0.05)。观察组患者阴道出血、周围组织受损发生率显著低于对照组(P<0.05)。结论阴式病灶切除联合子宫壁修补术治疗CSP,可减少术中出血量,降低血清β-hCG水平及并发症发生率,提高临床治疗效果,促进患者更快康复。
Objective To explore the efficacy of vaginal lesion resection combined with uterine wall repair in the treatment of cesarean scar pregnancy(CSP)after cesarean section.Methods A total of 122 patients with CSP admitted to our hospital were selected and randomly divided into the control group(61 cases)and the observation group(61 cases).Patients in the control group were treated with uterine artery chemoembolization(UACE)combined with ultrasound-guided curettage,while patients in the observation group were treated with vaginal lesion resection combined with uterine wall repair.The perioperative index,serum beta-human chorionic gonadotropin(β-hCG)levels before surgery and 3 days,5 days,and 7 days after surgery,clinical efficacy,and complications of patients between the groups were compared.Results The operation time of patients in the observation group was significantly longer than that in the control group(P<0.05),and the amount of intraoperative blood loss,hospitalization cost,vaginal bleeding time,time to menstruation recovery,mass disappearance time,β-hCG normalizing time,and hospitalization time of patients in the observation group were significantly less/shorter than those in the control group(P<0.05).The serumβ-hCG levels of patients 3 days,5 days and 7 days after surgery in both groups were lower compared with those before surgery,and the observation group was lower than the control group,with statistically significant differences(P<0.05).The total effective rate in the observation group was 96.72%,significantly higher than that of 85.25%in the control group(P<0.05).The incidence of vaginal bleeding and surrounding tissue injury in the observation group was significantly lower than that in the control group(P<0.05).Conclusion The combination of vaginal lesion resection and uterine wall repair for the treatment of CSP can reduce the amount of intraoperative blood loss,reduce the serumβ-hCG levels and the incidence of complications,improve clinical treatment efficacy,and promote recovery of patients.
作者
金莉娜
翁雯婧
梁艳
潘新美
JIN Li-na;WENG Wen-jing;LIANG Yan;PAN Xin-mei(Daytime Operating Room,International Peace Maternal and Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine/Shanghai Key Laboratory of Embryo Original Diseases,Shanghai 200030,China;Central Operating Room,International Peace Maternal and Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine/Shanghai Key Laboratory of Embryo Original Diseases,Shanghai 200030,China;Department of Gynecology,International Peace Maternal and Child Health Hospital Affiliated to Shanghai Jiao Tong University School of Medicine/Shanghai Key Laboratory of Embryo Original Diseases,Shanghai 200030,China)
出处
《局解手术学杂志》
2024年第8期693-696,共4页
Journal of Regional Anatomy and Operative Surgery
基金
上海交通大学“医学转化交叉基金”(ZH8QNB17)。
关键词
阴式病灶切除
子宫壁修补术
子宫瘢痕妊娠
疗效
vaginal lesion resection
uterine wall repair
cesarean scar pregnancy
therapeutic effect
