摘要
目的探讨不孕年限对30岁以下育龄女性冻融胚胎移植(frozen-thawed embryo transfer,FET)结局的影响。方法回顾性分析生殖中心540例FET周期,根据临床妊娠与否,分临床妊娠组和非临床妊娠组;再按患者不孕年限分为四组:A组(1~2年)、B组(3~4年)、C组(5~6年)和D组(7~8年),分析比较各组的基础资料、临床妊娠结局的差异。结果各组间基础资料比较,年龄差异有统计学意义(P<0.05),其余均差异无统计学意义;C组的临床妊娠率(33.93%)和胚胎着床率(25%)均最低,但只有临床妊娠率的差异有统计学对意义(P<0.05);四组间的早期流产率差异无统计学意义(P>0.05)。结论不孕年限对30岁以下育龄女性FET的临床妊娠率有影响,但并不是随着不孕年限时间越长影响越显著。
Objective To investigate the influence of infertility duration on the outcomes of frozen-thawed embryo transfer(FET)in women under 30 years old.Methods A retrospective analysis was conducted on 540 FET cycles at reproductive center.The cycles were categorized into clinical pregnancy and non-clinical pregnancy groups based on the occurrence of clinical pregnancy.Furthermore,patients were stratified into four groups based on infertility duration:Group A(1-2 years),Group B(3-4 years),Group C(5-6 years),and Group D(7-8 years).Differences in baseline characteristics and clinical pregnancy outcomes among the groups were analyzed.Results Baseline characteristics showed statistical significance only in age differences among the groups(P<0.05),with no other significant differences.The clinical pregnancy rate(33.93%)and embryo implantation rate(25%)in group C were the lowest,but only the difference in clinical pregnancy rate was statistically significant(P<0.05).Early miscarriage rates did not show significant differences among the four groups.Conclusion Infertility duration has a discernible impact significant impact on clinical pregnancy rate of FET in women under 30 years old.However,the effect does not linearly increase with longer infertility duration.
作者
杜娟
张艳茹
刘兰香
DU Juan;ZHANG Yanru;LIU Lanxiang(Department of Reproductive Medicine,Wuxi People’s Hospital,Wuxi 214023,Jiangsu,China;Department of Reproductive Center,the 904th Hospital of Joint Logistic Support Force of PLA,Wuxi 214000,Jiangsu,China)
出处
《中国现代医生》
2024年第20期94-98,共5页
China Modern Doctor
关键词
冻融胚胎移植
临床妊娠率
着床率
早期流产率
Frozen-thawedembryotransfer
Clinical pregnancy rate
Implantation rate
Early miscarriage rate
