摘要
目的 探讨甲状腺功能评估中甲状腺功能五项指标联合检测的价值。方法 目的选取2021年12月—2022年12月临沂市人民医院收治的90例甲状腺功能异常患者,其中甲状腺功能亢进与甲状腺功能减退患者各45例,分别设为甲亢组、甲减组,选取同期45例健康体检者作为健康对照组。检测各组三碘甲状腺原氨酸(Triiodothyronine,T3)、游离甲状腺素(Free Thyroxine,FT4)、游离三碘甲状腺原氨(Free Triiodothyronine,FT3)、甲状腺素(Thyroid Hormone,T4)、促甲状腺激素(Thyroid Stimulating Hormone,TSH)水平并进行比较。结果 健康对照组T3、FT3、FT4、T4均低于甲亢组,均高于甲减组,差异有统计学意义(P均<0.05)。健康对照组TSH高于甲亢组,低于甲减组,差异有统计学意义(P均<0.05)。TSH与甲亢严重程度间呈负相关,T3、FT4、FT3、T4呈正相关(P均<0.05)。TSH与甲减严重程度间呈正相关,T3、FT3、FT4、T4呈负相关(r=0.648、-0.637、-0.449、-0.417、-0.408,P均<0.05)。结论 FT3、FT4、TSH、T3、T4检测在甲状腺功能异常患者病情评价中具有一定的应用价值。
Objective To explore the value of combined detection of five indicators of thyroid function in thyroid function assessment.Methods 90 patients with thyroid dysfunction,including 45 patients with hyperthyroidism and 45 patients with hypothyroidism,were purposely selected from Linyi People's Hospital from December 2021 to December 2022.They were divided into hyperthyroidism group and hypothyroidism group,respectively.45 healthy individuals who underwent physical examinations during the same period were selected as the healthy control group.The levels of triiodothyronine(T3),free thyroxine(FT4),free triiodothyronine(FT3),thyroid hormone(T4),and thyroid stimulating hormone(TSH) in each group were detected and compared.Results The detection levels of T3,FT3,FT4,and T4 of thyroid hormones in the healthy control group were lower than those in the hyperthyroidism group and higher than those in the hypothyroidism group,the differences were statistically significant(all P<0.05).The detection levels of TSH of thyroid hormones in the healthy control group was higher than that in the hyperthyroidism group and lower than that in the hypothyroidism group,the differencs were statistically significant(both P<0.05).There was a negative correlation between TSH and the severity of hyperthyroidism,vlule triiodothyronine(T3),free thyroxine(FT4),free triiodothyronine(FT3),and thyroid hormone(T4) showing a positive correlation(all P<0.05).There was a positive correlation between TSH and the severity of hypothyroidism,while T3,FT3,FT4,and T4 are negatively correlated(r=0.648,-0.637,-0.449,-0.417,-0.408,all P<0.05).Conclusion The detection of FT3,FT4,TSH,T3,and T4 has certain application value in evaluating the condition of patients with thyroid dysfunction.
作者
田可郡
肖自芳
邹莹
TIAN Kejun;XIAO Zifang;ZOU Ying(Department of Nuclear Medicine,People's Hospital of Linyi City,Linyi 276000,Shandong,China)
出处
《系统医学》
2024年第12期82-85,共4页
Systems Medicine
