摘要
目的探讨不同妊娠期与甲状腺激素水平的相关性。方法目的选取2020年1月—2023年12月潍坊市妇幼保健院收治的260例正常妊娠孕妇作为研究对象,依据不同妊娠期,将孕妇划分为妊娠早期孕妇组(n=87)、妊娠中期孕妇组(n=87)以及妊娠晚期孕妇组(n=86)。比较3组的甲状腺激素水平,采用Pearson相关性系数分析甲状腺激素水平与不同妊娠期的相关性。结果与妊娠早期组、妊娠中期组比较,妊娠晚期组的游离三碘甲状腺原氨酸(Free Triiodothyronine,FT3)、游离甲状腺素(Free Thyroxine,FT4)水平较低,促甲状腺激素(Thyroid Stimulating Tormone,TSH)水平较高,差异有统计学意义(P均<0.05);与妊娠早期组比较,妊娠中期组的FT3、FT4水平较低,TSH水平较高,差异有统计学意义(P均<0.05)。FT3、FT4水平与妊娠周期呈负相关(r=-0.562、-0.327,P均<0.05),TSH与妊娠周期呈正相关(r=0.669,P<0.05)。结论不同妊娠期孕妇的甲状腺激素水平存在差异,FT3、FT4水平与妊娠周期为负相关关系,TSH水平与妊娠周期为正相关关系。
Objective To investigate the correlation between different gestational periods and thyroid hormone levels.Methods 260 cases of normal pregnant women admitted to Weifang Maternal and Child Health Hospital from January 2020 to December 2023 were purposefully selected as the study subjects,and according to the different gestation peri-ods,the pregnant women were divided into early pregnancy group(n=87),mid-pregnancy group(n=87),and late preg-nancy group(n=86).The thyroid hormone levels of the three groups were compared,and the correlation between thy-roid hormone levels and different gestation stages was analyzed using the Pearson correlation coefficient.Results Com-pared with the early pregnancy group and the mid-pregnancy group,the late pregnancy group had lower levels of free triiodothyronine(FT3)and free thyroxine(FT4),and higher levels of thyroid stimulating hormone(TSH),and the differ-ences were statistically significant(all P<0.05).Compared with the early pregnancy group,the mid-pregnancy group had lower levels of FT3 and FT4 and higher levels of TSH,and the differences were statistically significant(all P<0.05).FT3 and FT4 levels were negatively correlated with gestational cycle(r=-0.562,-0.327,both P<0.05),and TSH was positively correlated with gestational cycle(r=0.669,P<0.05).Conclusion There are differences in thyroid hor-mone levels in pregnant women at different gestational periods,FT3 and FT4 levels are negatively correlated with ges-tational cycles,and TSH levels are positively correlated with gestational cycles.
作者
孙东明
SUN Dongming(Department of Laboratory,Weifang Maternal and Child Health Hospital,Weifang 261021,Shandong,China)
出处
《系统医学》
2024年第12期161-163,共3页
Systems Medicine
关键词
孕妇
健康育龄女性
甲状腺激素水平
检验结果
Pregnant women
Healthy women of reproductive age
Thyroid hormone levels
Test results
