摘要
目的探究临床治疗急性湿疹湿热内蕴证患者时予以维生素E乳联合金蝉止痒胶囊治疗的效果及安全性。方法90例急性湿疹湿热内蕴证患者,以随机数字表法分为研究组与对照组,各45例。研究组采用维生素E乳联合金蝉止痒胶囊治疗,对照组实施常规治疗。对比两组患者语言评分法(VRS)评分、湿疹面积及严重程度指数(EASI)评分、治疗效果、不良反应发生率。结果研究组治疗后14、28 d的VRS评分分别为(1.29±0.24)、(0.65±0.24)分,均较对照组的(2.19±0.29)、(1.29±0.31)分更低,差异有统计学意义(P<0.05)。研究组治疗后14、28 d的EASI评分分别为(1.17±0.32)、(0.52±0.17)分,均较对照组的(2.31±0.42)、(1.32±0.27)分更低,差异有统计学意义(P<0.05)。研究组治疗总有效率(97.78%)较对照组(84.44%)更高,差异有统计学意义(P<0.05)。研究组不良反应发生率(4.44%)较对照组(17.78%)更低,差异有统计学意义(P<0.05)。结论临床使用维生素E乳联合金蝉止痒胶囊治疗急性湿疹湿热内蕴证患者疗效显著,用药后能够有效缓解患者肢体瘙痒程度,提高患者舒适度,减少腹泻、食欲减退等不良反应情况,确保患者尽早恢复健康,适合将其推广至基层医疗机构,值得临床使用。
Objective To explore the effect and security of vitamin E emulsion combined with Jinchan Zhiyang Capsules for acute eczema(damp heat accumulation syndrome).Methods 90 patients with acute eczema(damp heat accumulation syndrome)were randomly divided into a study group and a control group using a random number table method,each with 45 cases.The study group received treatment with vitamin E emulsion and Jinchan Zhiyang Capsules,while the control group received conventional treatment.The verbal rating scale(VRS)score,eczema area severity index(EASI)score,treatment effects,adverse reactions were compared between the two groups.Results The VRS scores of the study group on 14 and 28 d after treatment were(1.29±0.24)and(0.65±0.24)points,which were lower than(2.19±0.29)and(1.29±0.31)points of the control group,and the difference was statistically significant(P<0.05).The EASI scores of the study group on 14 and 28 d after treatment were(1.17±0.32)and(0.52±0.17)points,which were lower than(2.31±0.42)and(1.32±0.27)points of the control group,and the difference was statistically significant(P<0.05).The total effective rate of the study group(97.78%)was higher than that of the control group(84.44%),and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the study group(4.44%)was lower than that in the control group(17.78%),the difference was statistically significant(P<0.05).Conclusion The clinical use of vitamin E emulsion combined with Jinchan Zhiyang Capsule has a significant therapeutic effect on patients with acute eczema(dampness heat accumulation syndrome).It can effectively alleviate the degree of limb itching,improve patient comfort,reduce adverse reactions such as diarrhea and loss of appetite,ensure early recovery of patients,and is suitable to promote it to grassroots medical institutions.It is worth clinical use.
作者
李新
LI Xin(Linqing People's Hospital,Liaocheng 252600,China)
出处
《中国现代药物应用》
2024年第14期34-38,共5页
Chinese Journal of Modern Drug Application
关键词
急性湿疹
湿热内蕴证
金蝉止痒胶囊
瘙痒程度
安全性
Acute eczema
Damp heat accumulation syndrome
Jinchan Zhiyang Capsules
Itching severity
Security
