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甲巯咪唑与丙硫氧嘧啶治疗甲亢患者的疗效比较研究

A Study on the Therapeutic Effect of Methylimidazole and Propylthiouracil in Patients with Hyperthyroidism
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摘要 分析比较甲巯咪唑与丙硫氧嘧啶治疗甲亢患者的效果。选取2022年7月-2023年6月山东省菏泽市成武县人民医院收治的82例甲亢患者为研究对象,采用电脑随机法将患者分为研究组和对照组,每组各41例。对照组患者接受丙硫氧嘧啶治疗,研究组患者接受甲巯咪唑治疗,比较两组患者治疗效果。结果显示,研究组患者治疗总有效率高于对照组(P<0.05);治疗后,研究组患者各项甲状腺功能指标和肝功能指标均优于对照组(P<0.05);研究组患者不良反应总发生率明显低于对照组(P<0.05)。研究发现,甲巯咪唑治疗甲亢患者效果更好,有助于改善患者的甲状腺功能,减少对患者肝功能的损伤,治疗安全性较高,值得推广应用。 Analyze the efficacy of methylimidazole and propylthiouracil in the treatment of hyperthyroidism patients.82 hyperthyroidism patients admitted to Chengwu County People’s Hospital in Heze City,Shandong Province from July 2022 to June 2023 were selected as the research subjects.The patients were randomly divided into a study group and a control group using computer randomization,with 41 patients in each group.The control group received treatment with pyrimethamine,while the study group received treatment with methimazole.The treatment effects of the two groups of patients were compared.The results showed that the total effective rate of treatment in the study group was higher than that in the control group(P<0.05);After treatment,all thyroid and liver function indicators in the study group were better than those in the control group(P<0.05);The total incidence of adverse reactions in the study group was significantly lower than that in the control group(P<0.05).Research has found that methimazole is more effective in treating hyperthyroidism,helping to improve thyroid function,reduce damage to liver function,and has higher treatment safety.It is worth promoting and applying.
作者 徐晖 Xu Hui(Endocrinology Department,Chengwu People’s Hospital,Heze,Shandong 274200)
出处 《科技与健康》 2024年第13期69-72,共4页 Technology and Health
关键词 甲亢 甲巯咪唑 丙硫氧嘧啶 甲状腺功能 肝功能 hyperthyroidism methioimidazole propyl thiouracil thyroid function liver function
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