摘要
【目的】探讨芩膏消积汤治疗小儿消化不良的临床疗效及对其胃肠功能指标的影响。【方法】选取2021年1月至2022年3月两院收治的124例消化不良患儿,根据随机数字表法将其分为观察组(采用多潘立酮联合芩膏消积汤治疗)和对照组(采用多潘立酮治疗),每组62例。比较两组临床疗效,治疗前后中医证候积分、胃肠激素水平、胃动力变化情况。【结果】观察组总有效率为90.32%(56/62),高于对照组的75.81%(47/62),差异有统计学意义(χ^(2)=4.644,P<0.05)。治疗后,两组早饱、恶心、腹胀、嗳气等各项评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗后,两组患儿血清胃泌素(GAS)、胃动素(MTL)、胃饥饿素(GHR)水平均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。治疗后,两组胃窦收缩频率及收缩幅度显著高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。【结论】芩膏消积汤治疗小儿消化不良的临床疗效显著,可有效改善患儿胃肠激素水平,提升胃动力学指标水平。
【Objective】To explore the clinical efficacy of Qingao Xiaojitang in treating pediatric digestive disorders and its impact on gastrointestinal function indicators.【Methods】A total of 124 children with digestive disorders admitted to two hospitals from January 2021 to March 2022 were selected and randomly divided into an observation group(treated with domperidone combined with Qingao Xiaojitang)and a control group(treated with domperidone)using a random number table method,with 62 cases in each group.Two groups were compared in terms of clinical efficacy,TCM syndrome scores,gastrointestinal hormone levels,and changes in gastric motility before and after treatment.【Results】The total effective rate of the observation group was 90.32%(56/62),which was higher than the control group's 75.81%(47/62),and the difference was statistically significant(χ^(2)=4.644,P<0.05).After treatment,the scores of early satiety,nausea,abdominal distension,belching,etc.in both groups were lower than before treatment,and the observation group was lower than the control group,with a statistically significant difference(P<0.05).After treatment,the levels of MTL,GAS,and GHR in both groups of children were higher than before treatment,and the observation group was higher than the control group,with statistical significance(P<0.05).After treatment,the frequency and amplitude of gastric contraction waves in both groups were significantly higher than before treatment,and the observation group was higher than the control group,with a statistically significant difference(P<0.05).【Conclusion】Qingao Xiaojitang has significant clinical efficacy in treating pediatric digestive disorders,effectively alleviating gastrointestinal hormone levels and improving gastric motility indicators.
作者
赵彩红
丛明慧
方堃
侯红
ZHAO Caihong;CONG Minghui;FANG Kun(Qingdao Maternal and Child Health and Family Planning Service Center,Qingdao Shandong 266000)
出处
《医学临床研究》
CAS
2024年第7期984-986,990,共4页
Journal of Clinical Research
