摘要
目的:通过优化固相萃取(SPE)等各项参数,建立固相萃取纯化静脉留置针中双酚A(BPA)含量样品的处理方法。方法:样品经固相萃取柱净化并富集BPA,采用液质联用法(HPLC-MS/MS)测定。结果:建立了一种HPLC-MS/MS法测定静脉留置针中BPA含量样品的固相萃取方法。结论:该方法条件优良,可有效纯化和富集静脉留置针中的痕量BPA,便于准确测定样品中BPA的含量。
Objective:To establish a method for extraction-purification-quantitative determination of bisphenol A(BPA)in indwelling needles by optimizing the parameters of solid phase extraction(SPE).Methods:BPA was purified and enriched by SPE column and determined by HPLCMS/MS.Results:A solid phase extraction method was established for the determination of BPA content in intravenous catheters using HPLC-MS/MS.Conclusion:The method is suitable for the extraction and enrichment of BPA from indwelling needles and the determination of target compounds in samples.
作者
朱雪飞
程怡洁
王紫芸
苟彦彦
许静远
刘慧
Zhu Xuefei;Cheng Yijie;Wang Ziyun;Gou Yanyan;Xu Jingyuan;Liu Hui(Yangzhou Center for Food and Drug Control,Jiangsu,225000;Changshu Hospital Affi liated to Suzhou University,Jiangsu,215500;School of Biology and Food Engineering,Changshu Institute of Technology,Jiangsu,215500)
出处
《当代化工研究》
CAS
2024年第15期78-80,共3页
Modern Chemical Research
基金
江苏省市场监督管理局科技计划项目“静脉留置针中双酚A的残留情况及静脉注射液对静脉留置针中双酚A迁出影响的研究”(项目编号:KJ21125070)。
