摘要
目的探讨超声血流参数对甲状腺癌患者淋巴结转移的诊断价值。方法选取110例甲状腺癌患者和110例健康体检者,分别作为观察组和健康组,所有受试者均进行彩色多普勒超声检查。比较观察组和健康组的超声血流参数[收缩期峰值流速(PSV)、阻力指数(RI)、搏动指数(PI)、收缩期峰值流速/舒张末期流速(S/D)]。根据是否发生淋巴结转移将观察组患者分为淋巴结转移组(n=59)和无淋巴结转移组(n=51),比较两组患者的超声血流参数。绘制受试者工作特征(ROC)曲线,计算曲线下面积(AUC),分析PSV、PI、RI、S/D单独及联合检测对甲状腺癌患者淋巴结转移的诊断价值。结果观察组患者的PSV、S/D均明显高于健康组,PI、RI均明显低于健康组,差异均有统计学意义(P﹤0.01)。淋巴结转移组患者的PSV、S/D均明显高于无淋巴结转移组,PI、RI均明显低于无淋巴结转移组,差异均有统计学意义(P﹤0.01)。PSV、PI、RI、S/D联合检测诊断甲状腺癌患者淋巴结转移的AUC、灵敏度、特异度分别为0.905、96.12%、90.64%,均高于各指标单独检测。结论甲状腺癌患者PSV、S/D偏高,PI、RI偏低,PSV、PI、RI、S/D联合检测对甲状腺癌患者淋巴结转移具有较高的诊断价值,可为临床医师制订治疗方案提供科学的参考依据。
Objective To analyze the diagnostic value of ultrasound blood flow parameters for lymph node metastasis in patients with thyroid cancer.Method A total of 110 thyroid cancer patients and 110 healthy subjects were selected as observation group and healthy group,respectively.All subjects underwent color Doppler ultrasonography examination.The ultrasound blood flow parameters[peak systolic velocity(PSV),resistance index(RI),pulsation index(PI),peak systolic velocity/end diastolic velocity(S/D)]of the observation group and the healthy group were compared.Patients in the observation group were divided into lymph node metastasis group(n=59)and non-lymph node metastasis group(n=51)according to whether lymph node metastasis occurred,and the ultrasound blood flow parameters of the two groups were compared.The receiver operating characteristic(ROC)curve was plotted,the area under the curve(AUC)was calculated,and the diagnostic value of PSV,PI,RI,S/D single and combined detection for lymph node metastasis in thyroid cancer patients were analyzed.Result The PSV and S/D in observation group were significantly higher than those in healthy group,and the PI and RI were significantly lower than those in healthy group,the differences were statistically significant(P<0.01).The PSV and S/D in lymph node metastasis group were significantly higher than those in non-lymph node metastasis group,and the PI and RI were significantly lower than those in non-lymph node metastasis group,the differences were statistically significant(P<0.01).The AUC,sensitivity and specificity of PSV,PI,RI and S/D combined detection in the diagnosis of lymph node metastasis in patients with thyroid cancer were 0.905,96.12%and 90.64%,respectively,which were higher than those of each index single detection.Conclusion The PSV and S/D are high in patients with thyroid cancer,while PI and RI are low.The combined detection of PSV,PI,RI and S/D has a high diagnostic value for lymph node metastasis in patients with thyroid cancer,and can provide a scientific reference for clinicians to make treatment plans.
作者
任锋
门永忠
李金生
REN Feng;MEN Yongzhong;LI Jinsheng(Department of Ultrasound Medicine,Nanyang Central Hospital,Nanyang 473000,He’nan,China)
出处
《癌症进展》
2024年第13期1460-1463,共4页
Oncology Progress
基金
河南省医学科技攻关计划联合共建项目(2018020984)。
关键词
超声血流参数
甲状腺癌
淋巴结转移
诊断价值
ultrasound blood flow parameter
thyroid cancer
lymph node metastasis
diagnostic value
