摘要
目的:观察10号与14号一次性无菌鼻胃肠管在食管癌放疗患者中的应用效果。方法:选取2022年3月—2023年5月于中国医学科学院北京协和医学院肿瘤医院深圳医院接受留置鼻胃肠管的食管癌放疗患者86例作为研究对象,用随机数字表法分为10号管组(n=32)和14号管组(n=54)。10号管组使用10号一次性无菌鼻胃肠管,14号管组使用14号一次性无菌鼻胃肠管。比较两组置管不良事件发生率、放射性食管炎发生情况、疼痛情况、营养水平。结果:10号管组置管不良事件总发生率低于14号管组(P=0.033)。两组放射性食管炎总发生率比较,差异无统计学意义(P>0.05);10号管组放射性食管炎≥3级发生率低于14号管组(P=0.014)。置管当天至出院时,10号管组数字分级法(NRS)评分低于14号管组(P<0.05)。置管前、置管后3 d(D3)、出院时,两组主要整体营养状况评量表(PG-SGA)评分比较,差异无统计学意义(P>0.05);D3,两组PG-SGA评分低于置管前(P<0.05);出院时,两组PG-SGA评分高于D3(P<0.05)。结论:食管癌放疗患者应用10号一次性无菌鼻胃肠管效果更佳,置管不良事件、放射性食管炎发生率低,疼痛较轻,且营养改善状况与14号管无显著差异。
Objective:To observe the application effect of No.10 and No.14 disposable aseptic naso-gastrointestinal tube in patients with esophageal cancer radiotherapy.Methods:A total of eighty-six patients with esophageal cancer who received indentation naso-gastrointestinal tube in Shenzhen Hospital of Cancer Hospital of Chinese Academy of Medical Sciences Peking Union Medical College from March 2022 to May 2023 were selected as the study objects.They were divided into 10 tube group(n=32)and 14 tube group(n=54)by random number table method.No.10 disposable sterile nasal gastrointestinal tube was used in 10 tube group,and No.14 disposable sterile nasal gastrointestinal tube was used in 14 tube group.The incidence of adverse events,radiation esophagitis,pain and nutritional level of the two groups were compared.Results:The total incidence of adverse events in the 10 tube group was lower than that in the 14 tube group(P=0.033);there was no significant difference in the total incidence of radiation esophagitis between the two groups(P>0.05);the incidence of grade 3 radiation esophagitis in 10 tube group was lower than that in 14 tube group(P=0.014);from the day of catheterization to the time of discharge,the digital grading(NRS)score of the 10 tube group was lower than that of the 14 tube group(P<0.05);there was no significant difference in major global nutritional status scale(PG-SGA)scores between the two groups before implantation,3 days after implantation(D3)and at discharge(P>0.05);D3,PG-SGA scores in two groups were lower than before catheterization(P<0.05);at discharge,PG-SGA scores were higher than D3 in both groups(P<0.05).Conclusion:No.10 disposable aseptic naso-gastrointestinal tube had better effect on patients receiving radiotherapy for esophageal cancer,with lower incidence of adverse events and radiation esophagitis,less pain,and no significant difference in nutritional improvement compared with No.14 tube.
作者
张新梅
路虹
韦碧红
秦迪
周洋媚
Zhang Xinmei;Lu Hong;Wei Bihong;Qin Di;Zhou Yangmei(National Cancer Center/National Clinical Research Center for Cancer/Shenzhen Hospital of Cancer Hospital of Chinese Academy of Medical Sciences Peking Union Medical College,Shenzhen 518000,Guangdong Province,China)
出处
《中外医药研究》
2024年第19期150-152,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
基金
中国医学科学院肿瘤医院深圳医院院内科研课题资助项目(编号:SZ2020MS010)。
关键词
食管癌
放疗
管饲
鼻胃肠管
Esophageal cancer
Radiotherapy
Tube feeding
Naso-gastrointestinal tube
