摘要
目的通过心电图的变化,评估瓜蒌薤白半夏汤化裁联合常规西药治疗冠心病的疗效。方法选择2021年1月至2021年9月来厦门市中医院就诊的70例冠心病心肌缺血患者,分为观察组(采取瓜蒌薤白半夏汤联合常规西药治疗)和对照组(采取常规西药治疗),每组各35例。比较两组患者心电图指标、心电图疗效、临床疗效和不良反应。结果治疗前,两组患者高频成分/低频成分(HighFrequency,HF/Low frequency,LF)比值、时域指标期间标准差(Standard Diviation of NN Ntervals,SDNN)、均值标准差(Standard Deviation of the Averages of Normal NN Intervals in all 5-minute Segments of the Entire Recording,SDANN)和差值均方的平方差(Root Mean Square of Successive Differences,RMSSD)均无显著差异。治疗2周后,两组HF/LF比值、SDNN、SDANN和RMSSD均明显增加(P<0.05);且和对照组相比,观察组HF/LF比值、SDNN、SDANN和RMSSD增加更明显(P<0.05)。经治疗后,观察组临床治疗有效率高于对照组(P<0.05)。治疗期间,两组不良反应发生率无差异(P>0.05)。结论瓜蒌薤白半夏汤联合常规西药治疗冠心病心肌缺血疗效显著,能有效改善冠心病患者心电图,减少临床症状且安全性较高。
Objective To evaluate the efficacy of Guanlou Xiebai Banxia Decoction modification combined with conventional western medicine in the treatment of coronary heart disease throughchanges in electrocardiogram.Methods 70 patients with coronary heart disease and myocardial ischemia who visited Xiamen Hospital of Traditional Chinese Medicine from January 2021 to September 2021 were divided into the observation group(Guanlou Xiebai Banxia Decoctioncombined with conventional western medicine,n=35)and the control group(conventional western medicine,n=35).The electrocardiographic indices,electrocardiographic efficacy,clinical symptom efficacy,and adverse reactions of the two groups were compared.Results Before treatment,there was no significant difference in high frequency component/low frequency component(HF/LF)ratio,time domain index standard deviation of normal-to-normal intervals(SDNN),standard deviation of the averages of normal NN intervalsin all 5-minute segments of the entire recording(SDANN),and root mean square of successive differences(RMSSD)of between the two groups;after 2 weeks of treatment,the HF/LF ratio,SDNN,and RMSSD of both groups all increased significantly,P<0.05;and compared with the control group,the observation group had a more significant increase in HF/LF ratio,SDNN,SDANN,and RMSSD,P<0.05.After treatment,the clinical symptom effective rate of the observation group was higher than that of the control group(P<0.05).During the treatment period,there was no difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Guanlou Xiebai Banxia Decoctioncombined with conventional western medicine has a significant therapeutic effect on coronary heart disease with myocardial ischemia,can effectively improve the electrocardiogram of patients with coronary heart disease,reduce clinical symptoms,and has a high safety profile.
作者
张卫娜
ZHANG Weina(Xiamen Traditional Chinese Medicine Hospital ECG Department,Xiamen 361000,China)
出处
《中华灾害救援医学》
2024年第6期656-659,共4页
Chinese Journal of Disaster Medicine
关键词
冠心病
心肌缺血
体征和症状
coronary disease
myocardial ischemia
signs and symptoms
