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补中益气汤加减联合无创通气治疗在慢性阻塞性肺疾病急性加重并呼吸衰竭中的应用效果

Application Effect of Buzhong Yiqi Decoction Combined with Noninvasive Ventilation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Complicated with Respiratory Failure
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摘要 目的探析临床治疗慢性阻塞性肺疾病(简称“慢阻肺”)急性加重并呼吸衰竭患者期间运用无创通气治疗联合补中益气汤加减的效果。方法选取金沙县人民医院呼吸与危重症医学科2022年5月至2023年12月间收治的慢阻肺急性加重并呼吸衰竭患者76例,依照随机抽签法分为对照组和研究组,各38例。对照组采用常规治疗+无创通气治疗,研究组在对照组治疗方案基础上联合应用补中益气汤加减治疗。对比分析两组临床疗效、中医证候积分、肺功能、血气分析相关数据。结果实施治疗后,研究组患者关于通气时间、ICU住院时间、总住院时间等比对照组短(P<0.05);研究组患者FVC(用力肺活量)、IC/TLC(深吸气量/肺总量)、DLCO/VA(单位肺泡容积一氧化碳弥散量)指标水平高于对照组(P<0.05);研究组血pH值、PaCO_(2)(动脉血二氧化碳分压)、PaO_(2)(动脉血氧分压)等血气分析指标优于对照组(P<0.05);研究组患者治疗总有效率高于对照组(P<0.05)。结论临床上为慢阻肺急性加重并呼吸衰竭患者合理提供无创辅助通气治疗联合补中益气汤加减其效果显著。 Objective To evaluate the effectiveness of non-invasive ventilation(NIV)combined with modified Bu Zhong Yi Qi Tang in treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD)patients with respiratory failure.Methods 76 AECOPD patients with respiratory failure admitted to the Respiratory and Critical Care Department of Jinsha County People's Hospital from May 2022 to December 2023 were selected as the study subjects.They were randomly divided into the control group(38 cases)and the study group(38 cases)using a lottery method.The control group received standard treatment and NIV,while the study group received the same treatment plus modified Bu Zhong Yi Qi Tang.The clinical efficacy,TCM syndrome scores,lung function tests(FVC,IC/TLC,DLCO/VA),and blood gas analysis data were compared between the two groups.Results After treatment,the study group showed significantly shorter ventilation time,ICU stay,and total hospitalization duration compared to the control group(P<0.05).Compared with the control group,the study group also had higher FVC,IC/TLC,and DLCO/VA values(P<0.05),as well as better pH,PaCO_(2),and PaO_(2) levels(P<0.05)in blood gas analysis.The overall treatment efficacy of the study group was superior to that of the control group(P<0.05).Conclusion In clinical practice,combining NIV with modified Bu Zhong Yi Qi Tang is effective in the treatment of AECOPD patients.
作者 谢恩艳 刘春兰 邓靖 XIE Enyan;LIU Chunlan;DENG Jing(Jinsha County People's HospitalRespiratory and Critical Care Medicine,Bijie 551800,China)
出处 《中华灾害救援医学》 2024年第6期678-681,共4页 Chinese Journal of Disaster Medicine
关键词 补中益气汤 肺疾病 慢性阻塞性 无创通气治疗 buzhong yiqi decoction pulmonary disease,chronic obstructive Non invasive ventilation therapy
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