摘要
目的观察加味温胆汤联合西药治疗幽门螺杆菌(Hp)相关性胃炎(HPAG)的效果。方法选取中医科门诊符合HPAG诊断的患儿100例,随机分为治疗组和对照组。对照组50例用奥美拉唑肠溶胶囊、阿莫西林胶囊、克拉霉素片口服治疗,治疗组在西药基础上加用中药加味温胆汤颗粒剂。观察两组治疗前和治疗2周后的胃炎症状变化、停药4周后Hp转阴率及临床疗效。结果治疗后,两组胃脘灼热疼痛差异无统计学意义(P>0.05);治疗组口干口苦、纳差、嗳气反酸、便秘等主要临床症状改善情况及Hp转阴率优于对照组,差异有统计学意义(P<0.05)。治疗组总有效率为90.0%(45/50),高于对照组的84.0%(42/50),差异有统计学意义(P<0.05)。结论中西医结合能提高HPAG的临床治疗总有效率。
Objective To observe the curative effect of modified Wendan decoction combined with Western medicine in the treatment of helicobacter pylori associated gastritis(HPAG).Methods A total of 100 children with HPAG were randomly divided into treatment group and control group.The control group of 50 cases was treated with omeprazole enteric capsules,amoxicillin capsules and clar⁃ithromycin tablets.On the basis of Western medicine,Wendan decoction was added in the treatment group.The changes of gastritis symptoms before and after 2 weeks of treatment,and Hp clearance rate after 4 weeks of drug withdrawal were observed in each group.Results After treatment,there was no statistically significant difference in epigastric burning and pain between the two groups(P>0.05),and the improvement of main clinical symptoms such as dry mouth,bitter mouth,poor appetite,eructation,constipation and Hp conversion rate in the treatment group were better than those in the control group,and the difference was statistically significant(P<0.05).The total effective rate of the treatment group was 90.0%(45/50),which was higher than that of the control group(84.0%,42/50),and the difference was statistically significant(P<0.05).Conclusion The combination of traditional Chinese and Western medi⁃cine can improve the total effective rate of clinical treatment of HPAG.
作者
陈红梅
高诗晴
林洁琪
程志涣
阮灵秀
陈辉清(指导)
CHEN Hongmei;GAO Shiqing;LIN Jieqi;CHENG Zhihuan;RUAN Lingxiu;CHEN Huiqing(Department of Traditional Chinese Medicine,Fuzhou Children’s Hospital,Fujian Province,Fuzhou 350005,China)
出处
《中国中医药现代远程教育》
2024年第19期53-55,共3页
Chinese Medicine Modern Distance Education of China
基金
福建省福州市科技计划项目【No.2021-S-195】
福建省卫生计生委名老中医药专家陈辉清传承工作室项目【No.闽卫办中医发明电〔2018〕216号】
国家中医药管理局全国名老中医药专家陈辉清传承工作室项目【No.国中医药办人教函〔2021〕270号】。
关键词
胃脘痛
幽门螺杆菌相关性胃炎
加味温胆汤
儿科学
中西医结合疗法
经方
epigastric pain
helicobacter pylori associated gastritis
modified Wendan decoction
pediatrics
therapy of integrated tra⁃ditional Chinese and Western medicine
classical prescription
