摘要
目的:探究人工骨浆联合同种异体骨治疗对四肢骨缺损患者愈合情况及生活质量的影响。方法:选取102例于2021年5月—2023年12月在赣南医科大学第二附属医院进行治疗的四肢骨缺损患者作为研究对象,进行回顾性分析。根据治疗方式的不同将患者分为异体骨组(n=46,给予单纯同种异体骨治疗)、联合组(n=56,给予人工骨浆联合同种异体骨治疗)。比较两组愈合情况、愈合效果及生活质量。结果:联合组愈合时间早于异体骨组,差异有统计学意义(P<0.05)。两组并发症发生率比较,差异无统计学意义(P>0.05)。联合组和异体骨组术前VAS评分比较,差异无统计学意义(P>0.05);联合组和异体骨组术后24 h VAS评分较术前均降低,且联合组术后24 h VAS评分低于异体骨组,差异均有统计学意义(P<0.05)。联合组术后3个月X射线评分高于异体骨组,差异有统计学意义(P<0.05)。联合组和异体骨组术前健康调查量表36(SF-36)评分比较,差异均无统计学意义(P>0.05);联合组和异体骨组术后3个月SF-36评分均较术前升高,且联合组术后3个月SF-36评分均高于异体骨组,差异均有统计学意义(P<0.05)。结论:与单纯同种异体骨治疗相比,人工骨浆联合同种异体骨治疗四肢骨缺损,患者愈合时间短、术后疼痛感轻,有助于生活质量提高,且安全性高。
Objective:To explore the effect of artificial bone grafts combined with allogeneic bone therapy on the healing condition and quality of life of patients with limb bone defects.Method:A total of 102 patients with limb bone defects who were treated in the Second Affiliated Hospital of Gannan Medical University from May 2021 to December 2023 were selected as the research objects and analyzed retrospectively.Patients were divided into allogeneic bone group(n=46,given simple allogeneic bone therapy)and combined group(n=56,given artificial bone grafts combined with allogeneic bone therapy)according to different treatment methods.The healing condition,healing effect and quality of life of two groups were compared.Result:The healing time of combined group was earlier than that of allogeneic bone group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of complications between two groups(P>0.05).There was no significant difference in preoperative VAS scores between the combined group and the allogeneic bone group(P>0.05).VAS scores of combined group and allogeneic bone group 24 h after surgery were lower than those before surgery,and VAS scores of combined group 24 h after surgery was lower than that of allogeneic bone group,the differences were statistically significant(P<0.05).The X-ray scores of the combined group 3 months after surgery was higher than that of the allogeneic bone group,the difference was statistically significant(P<0.05).There were no significant differences in preoperative short form 36(SF-36)scores between the combined group and the allogeneic bone group(P>0.05).The SF-36 scores of the combined group and the allogeneic bone group 3 months after surgery were higher than those before surgery,and the SF-36 scores of the combined group 3 months after surgery were higher than those of the allogeneic bone group,the differences were statistically significant(P<0.05).Conclusion:Compared with simple allogeneic bone therapy,the combination of artificial bone grafts combined with allogeneic bone in the treatment of limb bone defects,patients has shorter healing time and less postoperative pain,which is helpful to improve the quality of life and has high safety.
作者
陈吉冰
邱苗
胡芳
CHEN Jibing;QIU Miao;HU Fang(Department of Orthopedics,the Second Affiliated Hospital of Gannan Medical University,Xinfeng 341600,China;不详)
出处
《中国医学创新》
CAS
2024年第25期34-38,共5页
Medical Innovation of China
基金
2022年度江西省教育厅科学技术研究项目(GJJ2201417)。
关键词
人工骨浆
同种异体骨
四肢骨缺损
愈合效果
生活质量
Artificial bone grafts
Allogeneic bone
Limb bone defects
Healing effect
Quality of life
