摘要
目的探讨强化血糖治疗联合牙周基础治疗对慢性牙周炎合并2型糖尿病患者的应用效果。方法选取2023年1月—2024年3月无锡市第二中医医院收治的80例慢性牙周炎合并2型糖尿病患者为研究对象,以治疗方法不同分为两组,各40例。对照组采用牙周基础治疗,观察组采用强化血糖治疗联合牙周基础治疗。比较两组血糖指标(空腹血糖、餐后2 h血糖、糖化血红蛋白)、牙齿相关指标(附着丧失、出血、菌斑指数)、炎症因子[白细胞介素-1β(interleukin-1β,IL-1β)、肿瘤坏死因子-α(tumor necrosis factor,TNF-α)]水平。结果治疗后,观察组空腹血糖、餐后2 h血糖、糖化血红蛋白水平均低于对照组,差异有统计学意义(P均<0.05)。治疗后,观察组附着丧失、出血和菌斑指数均低于对照组,差异有统计学意义(P均<0.05)。治疗后,观察组IL-1β、TNF-α水平均低于对照组,差异有统计学意义(P均<0.05)。结论强化血糖治疗联合牙周基础治疗对慢性牙周炎伴2型糖尿病患者的治疗效果较为理想,可降低血糖水平,改善牙周炎。
Objective To investigate the effect of intensive blood glucose therapy combined with periodontal basic therapy on patients with chronic periodontitis complicated with type 2 diabetes mellitus.Methods A total of 80 pa-tients with chronic periodontitis combined with type 2 diabetes mellitus who were admitted to Wuxi Second Hospital of Traditional Chinese Medicine from January 2023 to March 2024 were selected as the research objects.According to different treatment methods,they were divided into two groups,with 40 cases in each group.Control group treated with periodontal basic therapy,observation group treated by intensive blood glucose therapy combined periodontal ba-sic therapy.The levels of blood glucose indexes(fasting plasma glucose,2-hour postprandial plasma glucose,glycosyl-ated hemoglobin A1c),tooth-related indexes(attachment loss,bleeding and plaque index),inflammatory factors[inter-leukin-1β(IL-1β),tumor necrosis factor-α(TNF-α)]were compared between the two groups.Results After treat-ment,the fasting plasma glucose,2-hour postprandial plasma glucose,glycated hemoglobin A1c levels of the observa-tion group were lower than those of the control group,the differences were statistically significant(all P<0.05).After treatment,the attachment loss,bleeding and plaque indexes in the observation group were lower than those in the con-trol group,and the differences were statistically significant(all P<0.05).After treatment,the levels of IL-1βand TNF-αin the observation group were lower than those in the control group,and the differences were statistically significant(both P<0.05).Conclusion Intensive blood glucose therapy combined with periodontal basic therapy has ideal thera-peutic effect on patients with chronic periodontitis and type 2 diabetes mellitus,which can reduce blood glucose level and improve periodontitis.
作者
惠胜楠
薛秋波
徐仁杰
杨越萍
HUI Shengnan;XUE Qiubo;XU Renjie;YANG Yueping(Department of Stomatology,Wuxi Second Hospital of Traditional Chinese Medicine,Wuxi 214121,Jiangsu,China)
出处
《糖尿病新世界》
2024年第11期8-10,14,共4页
Diabetes New World
关键词
强化血糖治疗
牙周基础治疗
慢性牙周炎合并2型糖尿病
Intensive blood glucose therapy
Periodontal basic therapy
Chronic periodontitis combined with type 2 diabetes mellitus
