摘要
目的探讨藏医药治疗陈旧热症的配伍规律。方法查阅以陈旧热症为主题的31本相关藏医古籍文献,收集其记载的方剂,并根据《藏药晶镜本草》进行规范化处理,之后将整理好的数据导入中医传承计算平台,进行药物频次、关联规则、核心药物、“味性化味”分析。结果101首方剂中涉及组方药材204味,使用频次15次的有30味,其中排名前十位的药物依次为诃子、天竺黄、藏红花、檀香、余甘子、毛诃子、牛黄、兔耳草、丁香、獐牙菜。关联规则分析发现,当设置支持度0.40、置信度为0.90时得出药物组合共有8对,其中天竺黄-丁香等关联度最强,得到核心药物组合3组。出现频次最高的组合为诃子、余甘子、天竺黄、藏红花、兔耳草;药物六味以苦、甘为首,化味以苦味为首,十七效以稀、钝、稳为首。结论经数据挖掘发现陈旧热症药方组成中的高频药物整体围绕陈旧热症核心病机要素“热、虚、淤”进行论治,以清热解毒、滋养七精、活血化瘀为主进行了治疗,且药物配对遵从了藏医治疗陈旧热症三因协调、血瘀辩证、标本廉治的理论,为藏医药治疗陈旧热症提供了思路。
Objective To explore the compatibility law of Tibetan medicine in the treatment of old fever.Methods Thirty-one ancient Tibetan medicine books and literature with the theme of old fever were reviewedthe corresponding prescriptions recorded were collected and standardized according to the"Tibetan Medicine Crystal Mirror Materia Medica".Then,the sorted data was imported into the traditional Chinese medicine inheritance calculation platform for analysis of drug frequency,association rules,core drugs,and flavor transformation.Results Among the 101 prescriptions,there were 204 herbs involved,thirty of which were used more than 15 times.Among the thirty,the top ten drugs ranked in order were Myrobalan,Tabasheer,Saffron,Sandalwood,Phyllanthus emblica,Terminalia chebula,Bezoar,Lagotis yunnanensis,clove,and Swertia.The association rule analysis showed that when the support degree was set to≥0.40 and the confidence level was set to≥0.90,a total of 8 pairs of drug combinations were obtained.Among them,the strongest correlation was found in the combination of Tabasheer and Clove,resulting in 3 groups of core drug combinations,among which the combinations with the highest frequency were Myrobalan,Phyllanthus emblica,Tabasheer,Saffron,and Rabbit Ear Grass.The six flavors of the drug were mainly bitterness and sweetness,while the bitterness was the main flavor for flavor transformation,and the seventeen effects of Tibetan medicines were the dilution,dullness,and stability.Conclusion Through data mining,it was found that the high-frequency drugs in the composition of the prescription for old feverwere treated with the core pathogenesis elements of"heat,deficiency,and stasis",and the treatment was mainly carried out with heat clearing and detoxification,nourishing seven essences,and activating circulation and removing blood stasis.The drug pairing follows the theory of Tibetan medicine in the treatment of old fever,namely the coordination of the three causes,the dialectical treatment of blood stasis,and the treatment of both symptoms and the root cause,which provided ideas for the treatment of old fever by Tibetan medicine.
作者
桑吉草
扎西卓玛
多杰仁青
Sang Jicao;Zhaxi Zhuoma;Duojie Renqing(Tibetan Medicine University,Lhasa 850000,China;AffiliatedHospital of Tibetan Medicine University,Lhasa 850000,China)
出处
《西藏科技》
2024年第8期53-58,共6页
Xizang Science And Technology
基金
西藏藏医药大学博士点学科建设项目(BSDJS-TDJS-22-03)。
关键词
藏医
陈旧热症
中医传承计算平台
配伍规律
Tibetan medicine
Old fever
Traditional Chinese Medicine Inheritance Calculation Platform
Compatibility rules