摘要
目的探讨围产期抑郁与焦虑症状之间的动态变化情况及双向预测关系。方法本研究系前瞻性纵向研究,选取2022年10月1日至2023年10月1日于川北医学院附属医院产检的妊娠晚期孕妇进行追踪调查。分别在妊娠晚期(T_(1))与产后6周(T_(2))采用爱丁堡产后抑郁量表(Edinburgh Postnatal Depression Scale,EPDS)、焦虑自评量表(Self-rating Anxiety Scale,SAS)对研究对象进行心理评估。分析围产期抑郁与焦虑症状的筛查情况,进一步通过重复测量方差分析(ANOVA)及Pearson相关分析研究两者之间的差异及相关性,最后使用Mplus 8.3软件构建交叉滞后模型,分析在T_(1)与T_(2)的围产期抑郁与焦虑症状之间的纵向关联及预测方向。结果共纳入219例研究对象,T_(1)的抑郁与焦虑症状发生率分别为31.1%、6.8%,T_(2)的发生率分别为33.8%、10.5%;T_(1)与T_(2)抑郁、焦虑症状的发生率及SAS量表平均得分差异均有统计学意义(P<0.001);T_(1)与T_(2)的抑郁、焦虑症状之间均呈显著正相关(P<0.001),且T_(1)抑郁和焦虑症状均可显著正向预测T_(2)抑郁与焦虑症状(P<0.001)。结论在T_(1)与T_(2)两个时间段的围产期抑郁与焦虑症状之间存在相互影响和双向预测的关系。
Objective To explore the dynamic changes and bidirectional predictive relationship between perinatal depression and anxiety symptoms.Methods This study is a prospective longitudinal study,and the pregnant women in the third trimester of pregnancy who were examined in the Affiliated Hospital of North Sichuan Medical College from October 1,2022 to October 1,2023 were followed up.Edinburgh Postnatal Depression Scale(EPDS)and Self⁃rating Anxiety Scale(SAS)were used to evaluate the psychology of research subjects in the third trimester of pregnancy(T_(1))and six weeks after delivery(T_(2))respectively.Analyzed the screening of perinatal depression and anxiety symptoms,and the differences and correlation between them were further studied by repeated measurement analysis of variance(ANOVA)and Pearson correlation analysis.Finally,a cross⁃lag model was constructed by using Mplus 8.3 software to analyze the vertical correlation and prediction direction between perinatal depression and anxiety symptoms at T_(1) and T_(2).Results A total of 219 subjects were included.The incidence rates of depression and anxiety symptoms were 31.1%and 6.8%respectively at T_(1),33.8%and 10.5%at T_(2).The incidence of depression and anxiety symptoms and the average score of SAS between T_(1) and T_(2) were statistically significan(P<0.001).There was a significant positive correlation between T_(1) and T_(2) symptoms of depression and anxiety(P<0.001),and symptoms of depression and anxiety at T_(1) can significantly positively predict symptoms of depression and anxiety at T_(2)(P<0.001).Conclusions There is a relationship of mutual influence and bidirectional prediction between depression and anxiety of pregnant women in T_(1) and T_(2).
作者
谭欣林
黄玥
甘艳琼
袁玉红
廖宇佳
田小兵
漆洪波
石琪
Tan Xinlin;Huang Yue;Gan Yanqiong;Yuan Yuhong;Liao Yujia;Tian Xiaobing;Qi Hongbo;Shi Qi(Department of Obstetrics,Affiliated Hospital of North Sichuan Medical College,Nanchong Sichuan 637000;North Sichuan Medical College,Nanchong Sichuan 637000;Department of Clinical Psychology,Nanchong Psychosomatic Hospital,Nanchong Sichuan 637770;Department of Obstetrics and Gynaecology,Women and Children Hospital Affiliated to Chongqing Medical University,Chongqing 401147,P.R.China)
出处
《中国计划生育和妇产科》
2024年第9期75-79,共5页
Chinese Journal of Family Planning & Gynecotokology
基金
国家工业和信息化部、国家卫生健康委员会《5G+医疗健康应用试点项目》批准立项项目(项目编号:JKZX2022-5G03)。
关键词
围产期
抑郁
焦虑
交叉滞后分析
perinatal
depression
anxiety
cross⁃lagged analysis
