摘要
卒中后抑郁(post-stroke depression,PSD)是卒中的一种重要精神并发症,累及近1/3的卒中患者,严重影响患者功能恢复和生活质量,并且与卒中患者病死率增高相关。传统的抗抑郁治疗方法包括药物治疗和心理治疗,但可能存在不良反应、耐受性或效果有限等问题。重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)作为一种非侵入性神经调控技术,为PSD患者提供了一种新的治疗选择。文章对rTMS在PSD治疗中的应用及其可能的机制进行综述。
Post-stroke depression(PSD)is an important mental complication of stroke,affecting nearly 1/3 of stroke patients,seriously affecting patients'functional recovery and quality of life,and is associated with increased mortality of stroke patients.Traditional antidepressant treatments include medication and psychotherapy,but there may be problems with adverse reactions,tolerance,or limited effectiveness.Repetitive transcranial magnetic stimulation(rTMS),as a non-invasive neuroregulatory technique,offers a new treatment option for patients with PSD.This article reviews the application of rTMS in the treatment of PSD and its possible mechanism.
作者
范祥柱
李晨晨
曹自为
何晓璐
李飞
张持
Fan Xiangzhu;Li Chenchen;Cao Ziwei;He Xiaolu;Li Fei;Zhang Zhi(Department of Neurology,The Second People's Hospital of Hefei,Hefei 230011,China)
出处
《国际脑血管病杂志》
2024年第5期374-379,共6页
International Journal of Cerebrovascular Diseases
基金
合肥市关键共性技术研发项目(GJ2022SM07)。
关键词
卒中
抑郁症
经颅磁刺激
抗抑郁药
Stroke
Depression
Transcranial magnetic stimulation
antidepressant
