摘要
金钱草含有黄酮类、苷类、鞣质、挥发油、氨基酸等多种活性成分,具有利胆利尿、排石、抑菌、抗炎、抗感染等药理作用,且中药种质资源丰富,具有较好的开发潜力。概括了金钱草当前的质量控制现状,并基于质量标志物(Quality marker,Q-Marker)的概念从植物名称关系、药用配伍、传统功效、传统药性、可预测化学成分、新的功效、不同产地等7个方面进行预测分析。得出可将绿原酸、芦丁、槲皮素-3-O-葡萄糖苷、异鼠李素等化学有效成分作为金钱草的质量标志物的预测成分,以期为金钱草的质量控制研究及建立质量标准提供参考。
Jinqiancao(Lysimachiae Herba)contains various active ingredients such as flavonoids,glycosides,tannins,volatile oils,amino acids,etc.It has pharmacological effects such as promoting function of gallbladder and urination,stone excretion,antibacterial,anti-inflammatory and anti infective effects.Moreover,it has abundant germplasm resources and good development potential.This article summarized the current quality control status of Jinqiancao(Lysimachiae Herba)and conducted the predictive analysis based on the concept of quality marker from seven aspects,including plant phylogeny,medicinal compatibility,traditional efficacy,traditional medicinal properties,predictable chemical composition,new efficacy and different origins.It can be concluded that chlorogenic acid,rutin,quercetin-3-o-glucoside,isorhamnetin and other chemical active ingredients can be used as the predictive components of quality markers of Jinqiancao(Lysimachiae Herba),in order to provide reference for quality control research and establishment of quality standards of Jinqiancao(Lysimachiae Herba).
作者
杨蒙恩
李彦冉
葛君玺
秦格
苗艳艳
苗明三
YANG Mengen;LI Yanran;GE Junxi;QIN Ge;MIAO Yanyan;MIAO Mingsan(School of Pharmacy,Henan University of Chinese Medicine,Zhengzhou 450046,Henan,China)
出处
《中华中医药学刊》
CAS
北大核心
2024年第10期112-117,共6页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金项目(82274119)
国家中医药管理局岐黄学者项目(国中医药人教函2022-6)
河南省重大专项(221100310400)
河南省重大公益专项(201300310100)。
关键词
金钱草
质量标志物
质量控制
Jinqiancao(Lysimachiae Herba)
quality markers
quality control
