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左甲状腺素钠片治疗妊娠期亚临床甲减的效果及对妊娠结局的影响

Effect of Levothyroxine Sodium Tablets on Subclinical Hypothyroidism and Pregnancy Outcomes During Pregnancy
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摘要 目的探讨左甲状腺素钠片在妊娠期亚临床甲减中的疗效和对妊娠结局的影响。方法选取2020年1月—2023年8月本院收治的妊娠期亚临床甲减孕妇55例为研究对象,并按照随机数字法分成对照组(27例)和观察组(28例)。其中,对照组孕妇接受常规治疗,观察组孕妇采取左甲状腺素钠片治疗。对比两组孕妇治疗效果以及甲状腺素水平和不良妊娠结局发生率。结果观察组治疗效果高于对照组,组间差异有统计学意义(P<0.05)。治疗前,两组孕妇甲状腺素水平对比,差异无统计学意义(P>0.05);治疗后,观察组甲状腺素水平优于对照组,组间差异有统计学意义(P<0.05)。治疗后,观察组孕妇不良妊娠结局发生率低于对照组,组间差异有统计学意义(P<0.05)。结论临床实践证实,对妊娠期亚临床甲减采用左甲状腺素钠片进行治疗,能够显著改善患者的甲状腺功能,且治疗效果确切可靠。此外,该治疗方法还有助于降低不良妊娠结局的发生率,对提高妊娠期女性的健康水平具有重要意义,因此在临床上具有显著的应用价值。 Objective To explore curative effect of levothyroxine sodium tablets in subclinical hypothyroidism during pregnancy and their effect on pregnancy outcomes.Methods The paper chose 55 pregnant women with subclinical hypothyroidism during pregnancy in our hospital from January 2020 to August 2023,and divided them into control group of 27 cases and observation group of 28 cases randomly with digital method.Control group was treated with routine treatment,and observation group with levothyroxine sodium tablets.Curative effect,thyroid hormone levels,and incidence of adverse pregnancy outcomes were compared between two groups.Results Curative effect in observation group was higher than control group(P<0.05),with statistical significance.Before treatment,there was little difference in thyroid hormone levels between groups,(P>0.05).After treatment,thyroid hormone levels in observation group were better than control group(P<0.05),with statistical significance.Incidence of adverse pregnancy outcomes in observation group were lower than control group after treatment(P<0.05),data were statistically significant.Conclusion Levothyroxine sodium tablets can further improve thyroid function of patients subclinical hypothyroidism during pregnancy,reduce adverse pregnancy outcomes with definite clinical effect,which has significant clinical significance.
作者 黄霞倩 HUANG Xiaqian(Obstetrics Department,Changshu City the First People's Hospital,Changshu,Jiangsu 215500)
出处 《智慧健康》 2024年第19期47-49,共3页 Smart Healthcare
关键词 妊娠期亚临床甲减 左旋甲状腺钠片 妊娠结局 Subclinical hypothyroidism during pregnancy levothyroxine sodium tablets Pregnancy outcome
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