摘要
目的:分析盐酸舍曲林联合复方甘菊利多卡因凝胶在早泄治疗中的应用效果。方法:选取2021年6月至2023年5月在我院就诊的早泄患者80例,分组依据为计算机随机法,对照组实施复方甘菊利多卡因凝胶治疗,观察组实施盐酸舍曲林联合复方甘菊利多卡因凝胶治疗,对比两组患者阴道内射精潜伏时间(IELT)、每周成功性生活次数、早泄诊断量表(PEDT)评分、不良反应发生情况。结果:治疗后,观察组患者IELT、每周成功性生活次数[(5.39±1.17)min、(1.82±0.45)次/周]显著优于对照组[(2.49±0.73)min、(0.93±0.19)次/周,P<0.05];治疗前两组PEDT评分对比无显著差异(P>0.05),治疗后观察组患者PEDT评分显著低于对照组[(7.42±2.04)分vs(9.85±2.36)分,P<0.05];两组不良反应发生率对比无显著差异(P>0.05)。结论:盐酸舍曲林联合复方甘菊利多卡因凝胶在早泄治疗中的应用效果显著,有效提高患者性生活质量,且并未明显增加不良反应发生率,安全性高,值得推广。
Objective:To investigate the effect of sertraline hydrochloride combined with compound chamomile lidocaine gel in the treatment of premature ejaculation(PE).Methods:We selected 80 cases of PE treated in our hospital from June 2021 to May 2023 and equally randomized them into a control and an observation group,the former medicated with compound chamomile lidocaine gel while the latter with sertraline hydrochloride in addition,both for 6 weeks.We recorded and compared the intravaginal ejaculation latency time(IELT),the number of successful sexual intercourses per week,the Premature Ejaculation Diagnostic Tool(PEDT)scores,and the incidence of adverse reactions between the two groups of patients.Results:After the treatment,the IELT was significantly longer([5.39±1.17]vs[2.49±0.73]min,P<0.05),the weekly number of successful sexual intercourses remarkably higher(1.82±0.45 vs 0.93±0.19,P<0.05)and the PEDT scores markedly lower(7.42±2.04 vs 9.85±2.36,P<0.05)in the observation than in the control group,but no statistically significant differences were observed in the baseline PEDT scores or the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Sertraline hydrochloride combined with compound chamomile lidocaine gel is definitely effective in the treatment of PE,which can significantly improve the patients’quality of sexual life,with a high safety and low incidence of adverse reactions.
作者
李树根
高尚
顾振卫
赵道华
江杰
陆晓婷
刘兰香
刘浩然
陈泽
LI Shu-gen;GAO Shang;GU Zhen-wei;ZHAO Dao-hua;JIANG Jie;LU Xiao-ting;LIU Lan-xiang;LIU Hao-ran;CHEN Ze(The Second People's Hospital of Wuzhong District,Suzhou,Jiangsu 215127,China)
出处
《中华男科学杂志》
CAS
CSCD
2024年第9期809-812,共4页
National Journal of Andrology
关键词
盐酸舍曲林
复方甘菊利多卡因凝胶
早泄
应用效果
sertraline hydrochloride
compound chamomile lidocaine gel
premature ejaculation
application effect
