摘要
目的研究黏膜下注射地塞米松对种植骨增量术后镇痛及消肿的疗效,并分析种植骨增量术后疼痛和肿胀的相关因素。方法收集2023年1月至2023年12月于南京医科大学附属口腔医院特诊科就诊的牙列缺损需实施骨增量(GBR或上颌窦内提升)的患者,测量并记录术后72 h内的疼痛和肿胀情况,以及可能的影响因素,包括性别、年龄、种植数量、手术时长、口腔卫生状况、FAC术前紧张程度及PSQ疼痛敏感性值,对两组不同时间的疼痛程度和肿胀程度进行差异比较,并对可能的影响因素进行皮尔森相关性及多元线性回归分析。结果给予地塞米松干预的患者疼痛程度在12 h起显著低于对照组,而肿胀评分在48 h开始显著低于对照组。相关性分析及回归分析显示,GBR术式对术后疼痛和肿胀有显著影响(r=0.348,P=0.030/r=0.441,P=0.005),其疼痛程度的线性回归模型同样具有统计学意义(R^(2)=0.126,P=0.030)。结论黏膜下注射地塞米松能够显著缓解种植骨增量术后患者的疼痛及肿胀不适,提高诊疗舒适度。
Objective To study the efficacy of submucosal injection of dexamethasone in analgesia and detumescence after incremental bone implantation,and to analyze the related factors of pain and swelling after incremental bone implantation.Methods Patients with dentition defect requiring bone increment(GBR or internal maxillary sinus lift)were collected from the Special Clinic of the Affiliated Stomatology Hospital of Nanjing Medical University from January 2023 to December 2023.Pain and swelling within 72 hours after surgery were measured and recorded,as well as possible influencing factors,including gender,age,number of implants,duration of surgery,and other factors.Oral health status,pre-FAC tension and PSQ pain sensitivity were compared between the two groups at different time.Pearson correlation and multiple linear regression analysis were performed for the possible influencing factors.Results Patients receiving dexamethasone intervention had significantly lower pain levels at 12 hours and significantly lower swelling scores at 48 hours.Correlation analysis and regression analysis showed that GBR had a significant effect on postoperative pain and swelling(r=0.348,P=0.030/r=0.441,P=0.005),and the linear regression model of pain degree was also statistically significant(R^(2)=0.126,P=0.030).Conclusion Submucosal injection of dexamethasone can significantly relieve the pain,swelling and discomfort of patients after incremental bone implantation,and improve the comfort of diagnosis and treatment.
作者
何峰
朱虹
朱文卿
HE Feng;ZHU Hong;ZHU Wenqing(Department of Oral Special Consultation,Affiliated Stomatological Hospital of Nanjing Medical University,State Key Laboratory Cultivation Base of Research,Prevention and Treatment for Oral Diseases,Jiangsu Province Engineering Research Center of Stomatological Translational Medicine,Nanjing 210029,China)
出处
《口腔医学》
CAS
2024年第9期652-657,共6页
Stomatology
基金
国家自然科学基金青年项目(82201096)。
关键词
种植骨增量
地塞米松
疼痛因素
肿胀程度
bone implant increment
dexamethasone
pain factor
degree of swelling
