摘要
目的:探究双胎妊娠孕妇并发妊娠期高血压的危险因素及其对妊娠结局的影响。方法:选择2019年7月至2023年7月收治的130例双胎妊娠孕妇进行回顾性研究,以其中42例患有妊娠高血压的双胎妊娠孕妇为观察组,并同时选取88例同期健康双胎妊娠孕妇作为对照组。比较2组研究对象分娩方式、不良妊娠结局及新生儿并发症情况,并采用logistic回归分析双胎妊娠孕妇妊娠高血压的危险因素。结果:观察组孕妇剖宫产率、不良妊娠结局发生率、新生儿并发症发生率均高于对照组(P<0.05);单因素分析结果显示:是否为高龄妊娠、孕前体质量指数(BMI)、孕期体质量增长(GWG)、是否有妊娠高血压家族史、合并妊娠期糖尿病在双胎妊娠并发妊娠高血压分布中差异均有统计学意义(P<0.05~P<0.01)。多因素logistic回归分析显示:高龄妊娠、孕前BMI高、有妊娠高血压家族史、合并妊娠期糖尿病均是不良妊娠结局的独立危险因素(P<0.05~P<0.01)。结论:双胎妊娠高血压孕妇剖宫产率、妊娠期并发症、不良妊娠结局风险更高。高龄妊娠、孕前BMI过高、有妊娠高血压家族史、合并妊娠期糖尿病是双胎妊娠并发妊娠高血压独立危险因素。
Objective:To investigate the risk factors of pregnancy-induced hypertension in twin pregnancies and its influence on pregnancy outcome.Methods:A retrospective study of 130 pregnant women with twin pregnancies admitted from July 2019 to July 2023 was conducted,42 pregnant women with pregnancy-induced hypertension were selected as the observation group,and 88 healthy pregnant women with twin pregnancies during the same period were selected as the control group.The methods of delivery,adverse pregnancy outcomes and neonatal complications were compared between two groups,and the risk factors of hypertension were analyzed by logistic regression analysis.Results:The rates of cesarean section,adverse pregnancy outcome and neonatal complications in the observation group were higher than those in control group(P<0.05).The results of univariate analysis showed that the differences of distribution of hypertension in twin pregnancies among older pregnancy,pre-pregnancy body mass index(BMI),gestational body mass increase(GWG),family history of pregnancy-induced hypertension and gestational diabetes mellitus were statistically significant(P<0.05 to P<0.01).The results of multivariate logistic regression analysis showed that the advanced pregnancy,high pre-pregnancy BMI,family history of pregnancy-induced hypertension and gestational diabetes mellitus were the independent risk factors of adverse pregnancy outcomes(P<0.05 to P<0.01).Conclusions:The risk of cesarean section,pregnancy complications and adverse pregnancy outcomes in hypertensive twins is higher.The advanced pregnancy,high BMI before pregnancy,family history of pregnancy-induced hypertension and gestational diabetes mellitus were the independent risk factors of twin pregnancy complicated with pregnancy-induced hypertension.
作者
范娟
冯小凤
FAN Juan;FENG Xiaofeng(Department of Gynaecology and Obstetrics,The Affiliated Chuzhou Hospital of Anhui Medical University,Chuzhou Anhui 239000,China)
出处
《蚌埠医学院学报》
CAS
2024年第9期1161-1164,1169,共5页
Journal of Bengbu Medical College
基金
安徽省滁州市卫生健康科研项目(CZWJ2022C002)。
关键词
妊娠期高血压
双胎妊娠
危险因素
不良妊娠结局
pregnancy-induced hypertension
twin pregnancy
risk factors
adverse pregnancy outcome
