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儿童肝母细胞瘤的CT特征与病理基础

CT Features and Pathological Basis of Neuroblastoma in Children
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摘要 目的 探讨儿童肝母细胞瘤CT的特征表现及其病理基础。方法回顾分析27例患儿经手术和/或穿刺病理证实为肝母细胞瘤的CT图像。结果27例肿块大小不一,最大径大于10cm者19例且凸向肝外生长;19例跨叶生长;24例肿瘤发生不同程度坏死(24/27);8例肿瘤内出现斑点状、砂粒状、片状钙化(8/27);10例肿瘤内部出血(10/27);增强扫描动脉期肿块呈不均质中等度强化,静脉期及延迟期强化逐渐消退;20例肿瘤对周围毗邻血管(肝右、中、左静脉、下腔静脉等)推压(20/27),3例肿瘤发生远处转移(3/27)。结论肝母细胞瘤发病率低,但结合其发病年龄、AFP值及CT特征性表现(肝脏巨大肿块,常凸出肝外,坏死、出血常见,肿块呈明显不均质强化),CT特征对临床医师制定治疗方案有重要的临床价值。 Objective To explore the CT featu res and pathological basis of hepatoblastoma.Methods 27 cases with hepatoblastoma confirmed by operation and/or pathology were retrospectively analyzed,including the CT examination data.Results The masses were various in size,the largest diameter larger than10cm in 19 cases and protruding extra hepatic growth;Cross-leaf growth in 19 cases;Different degrees of necrosis in 24 cases(24/27);Spotted,sand-grained,flaky calcification in 8 cases(8/27);Internal haemorrhage in 10 cases(10/27);Heterogeneous and moderate enhancement in arterial phase,and gradual regression in venous phase and delayed phase.The adjacent blood vessels(right,middle,left hepatic vein,inferior vena cava,etc.) were pressed in 20 cases(20/27),and distant metastasis occurred in 3 cases(3/27).Conclusion The incidence of hepatoblastoma is very low,but it is generally easy to make an accurate diagnosis according to the age of onset,the value of AFP and the cha racteristics of CT(Liver huge mass with protrusive extra hepatic growt h,internal necrosis,and hemorrhage,significant hete rogeneous enhancement),which is of important value for clinicians to choose treatment plans.
作者 刘燕 侯崇智 景彦博 郝跃文 LIU Yan;HOU Chong-zhi;JING Yan-bo;HAO Yue-wen(Department of Medical Imaging,Xidian Group Hospital,Xi'an 710077,Shaanxi Province,China;Department 1 of General Surgery,Xi'an Children's Hospital,Xi'an 710003,Shaanxi Province,China;Department of Imaging,Xi'an Children's Hospital,Xi'an 710003,Shaanxi Province,China)
出处 《中国CT和MRI杂志》 2024年第10期97-98,共2页 Chinese Journal of CT and MRI
基金 骨肉瘤化疗前后MR特征与术后肿瘤细胞坏死关联性研究(2023-JC-YB-635)。
关键词 肝母细胞瘤 儿童 计算机体层摄影术 病理 Hepatoblastoma Children CT(Computed Tomography) Pathology
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