摘要
目的评估经尿道前列腺等离子剜除术患者,围手术期维持阿司匹林抗血小板治疗的手术安全性。方法回顾性分析2017年1月至2023年12月连云港市中医院泌尿外科行经尿道前列腺等离子剜除术治疗的85例前列腺增生患者。分为阿司匹林组(围手术期维持阿司匹林抗血小板治疗,n=37)、对照组(术前1周停用阿司匹林,并于术后1周再次服用阿司匹林抗血小板治疗,n=48)。比较两组患者手术时间、切除前列腺体积、手术出血量、膀胱冲洗时间、国际前列腺症状评分(IPSS)、膀胱残余尿量(BVR)及最大尿流率(Qmax)。结果两组患者手术时间、切除前列腺体积、手术出血量及膀胱冲洗时间差异无统计学意义(P>0.05)。两组患者术后IPSS评分、BVR及Qmax差异无统计学意义(P>0.05)。两组患者均无输血病例,无再次手术病例,无心血管事件等并发症。与术前比较,两组术后3个月IPSS、BVR及Qmax明显改善(P<0.05),但阿司匹林组与对照组比较差异无统计学意义(P>0.05)。结论围手术期维持阿司匹林抗血小板治疗患者行经尿道前列腺等离子剜除术是安全有效的,没有增加围手术期出血等并发症的风险。。
Objective To evaluate the safety of perioperative maintenance of aspirin antiplatelet therapy in patients under-going transurethral plasmakinetic enucleation of the prostate.Methods 85 patients with benign prostatic hyperplasia who under-went transurethral plasma enucleation of the prostate in the Department of Urology,Lianyungang Hospital of traditional Chinese medi-cine from January 2017 to December 2023 were retrospectively analyzed.They were divided into aspirin group(perioperative mainte-nance of aspirin antiplatelet therapy,n=37),the control group(aspirin was stopped one week before surgery,and aspirin antiplatelet therapy was taken again one week after surgery,n=48).The surgical time,volume of resected prostate,surgical blood loss,bladder flushing time,International Prostate Symptom Score(IPSS score),bladder residual urine volume(BVR)and maximum urine flow(Qmax)were compared between the two groups.Results There was no significant difference in surgical time,volume of resected pros-tate,blood loss and bladder flushing time between the two groups(P>0.05).There was no significant difference in IPSS,BVR and Qmax be-tween the two groups(P>0.05).There were no cases of blood transfu-sion or unexpected secondary surgery,and no cardiovascular events or other complications in the two groups.The IPSS,BVR and Qmax of the two groups were significantly improved 3 months after the surgery compared with those before the surgery(P<0.05),but there was no significant difference between the aspirin group and the control group(P>0.05).Conclusion It is safe and effective to maintain as-pirin antiplatelet therapy in patients undergoing transurethral plasmakinetic enucleation of the prostate during the perioperative period,without increasing the risk of perioperative bleeding or other complications.
作者
王珩
徐向军
刘兆飞
张海涛
毛鹏飞
聂锐志
WANG Heng;XU Xiangjun;LIU Zhaofei;ZHANG Haitao;MAO Pengfei;NIE Ruizhi(Department of Urology,Lianyungang TCM Hospital Affiliated to Nanjing University of Chinese Medicine,Lianyun-gang 222004,Jiangsu,China)
出处
《医学研究与战创伤救治》
CAS
北大核心
2024年第7期724-728,共5页
Journal of Medical Research & Combat Trauma Care
基金
连云港市抗癌协会肿瘤防治科技发展计划项目(ZD202311)。
关键词
经尿道前列腺等离子剜除术
抗血小板治疗
阿司匹林
前列腺增生
transurethral plasmakinetic enucleation of prostate
antiplatelet therapy
aspirin
benign prostatic hyperplasia
