摘要
目的探讨多囊卵巢综合征(PCOS)患者应用优思明和达英-35治疗的临床效果。方法于2021年1月-2021年9月采集病例资料入档,对象为医院收治的PCOS患者共计纳入80例,纳入对象基于“随机数字表法”规范化分组处理,划分为对照组(予以达英-35治疗)与观察组(予以优思明治疗),每组纳入40例;观察对比两组症状改善率、激素水平变化、卵巢功能指标、血脂水平。结果治疗后,两组多毛、闭经、月经稀少、面部痤疮率明显下降,其中观察组更低(P<0.05);治疗后,两组E2、LH、FSH、T明显下降,其中观察组较对照组更低(P<0.05);治疗后,两组卵巢最大面积的平均卵巢直径、窦状卵泡数显著升高,其中观察组升高更明显(P<0.05);治疗后,两组T-CHO、HDL-C均明显升高(P<0.05),两组IDL-C治疗前后组内比较无显著差异(P>0.05),治疗后T-CHO、IDL-C水平组间对比(P>0.05)。结论PCOS患者予以优思明和达英-35治疗,两者均可改善高雄激素血症相关症状,调节性激素水平,保护卵巢功能,但优思明效果更突出。
Objective To investigate the clinical effect of Yasmin and Dain-35 in the treatment of polycystic ovary syndrome(PCOS).Methods A total of 80 PCOS patients admitted to the hospital were collected and recorded from January 2021 to September 2021.The patients were classified into control group(treated with Dain-35)and observation group(treated with Yasmin)based on the standardized grouping of"random number table method",with 40 cases in each group.The improvement rate of symptoms,hormone level,ovarian function index and blood lipid level were observed and compared between the two groups.Results After treatment,the rates of hirsutism,amenorrhea,menstruation and facial acne were significantly decreased in two groups,and the rates were lower in the observation group(P<0.05).After treatment,E2,LH,FSH and T in the two groups were significantly decreased,and the observation group was lower than the control group(P<0.05).After treatment,the mean ovarian diameter and the number of sinus follicles with the largest ovarian area were significantly increased in the two groups,and the increases were more obvious in the observation group(P<0.05).After treatment,T-CHO and HDL-C were significantly increased in the two groups(P<0.05),and there was no significant difference between the two groups before and after IDL-C treatment(P>0.05),and the levels of T-CHO and IDL-C were compared between the two groups after treatment(P>0.05).Conclusions Both Yasmin and Dain-35 can improve hyperandrogenemia related symptoms,regulate sex hormone levels and protect ovarian function in PCOS patients,but the effect of Yasmin is more prominent.
作者
吴姣姣
WU Jiao-jiao(Obstetrics and Gynecology Department,Xiaogan Hospital of Traditional Chinese Medicine,Xiaogan 432100,Hubei Province,China)
出处
《罕少疾病杂志》
2024年第10期90-91,102,共3页
Journal of Rare and Uncommon Diseases
