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真皮再生模板应用于糖尿病足溃疡创面愈合的研究进展

Application of Dermal Regeneration Template for Wound Healing of Dia⁃betic Foot Ulcers
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摘要 糖尿病足溃疡是糖尿病严重并发症之一,不仅加剧了患者的身体负担,还对其生活质量构成了严重威胁。临床上对糖尿病足溃疡进行清创治疗后,创面常难以愈合。随着组织工程技术的进步,真皮再生模板作为一种伤口愈合的新兴材料逐渐应用于各类急慢性伤口,可加速血管化进程,加快肉芽组织与类真皮组织生长,促进伤口愈合。本文旨在阐述真皮再生模板组织结构、作用机制、应用于糖尿病足溃疡的临床效果及其不足与展望,为真皮再生模板在糖尿病足溃疡患者中的应用提供有意义的参考。 Diabetic foot ulcers is one of the serious complications of diabetes,which not only aggravates the physical burden of patients,but also poses a serious threat to their quality of life.After clinical debridement and invasive treat-ment of diabetic foot ulcers,the wound surface is often difficult to heal.With the progress of tissue engineering tech-nology,dermal regeneration template,as an emerging material for wound healing,is gradually applied to various acute and chronic wounds,which can accelerate the process of vascularization,accelerate the growth of granulation tissue and dermal tissue,and promote wound healing.This paper aims to explain the tissue structure,mechanism of action,clinical effect of diabetic foot ulcers and its shortcomings,and provide meaningful reference for the application of der-mal regeneration template in patients with diabetic foot ulcers.
作者 郭士琪 周秀玲 程娜 薛静雅 GUO Shiqi;ZHOU Xiuling;CHENG Na;XUE Jingya(School of Nursing,Changchun University of Traditional Chinese Medicine,Changchun 130000,Jilin,China)
出处 《糖尿病新世界》 2024年第14期188-193,共6页 Diabetes New World
基金 吉林省科技发展计划重点研发项目(20230203070SF)。
关键词 真皮再生模板 糖尿病足 糖尿病足溃疡 Dermis regeneration template Diabetic foot Diabetic foot ulcers
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