摘要
目的探讨甲泼尼龙联合巴曲酶治疗突发性耳聋的临床效果及对血液流变学指标的影响。方法选取2020年6月-2023年12月我院收治的62例突发性耳聋患者,随机分为对照组和试验组,各31例。对照组给予甲泼尼龙治疗,试验组在对照组的基础上联合巴曲酶治疗。对比两组血液流变学指标、治疗有效性和不良反应情况。结果治疗前,两组血液流变学指标比较,差异无统计学意义(P0.05);治疗后,试验组患者血浆黏度、红细胞沉降率均低于对照组(P<0.05)。试验组患者治疗总有效率96.77%高于对照组74.19%(P<0.05),两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论突发性耳聋患者格欧甲泼尼龙联合巴曲酶治疗,可改善血液流变学指标,提高治疗效果,安全性高。
Objective To investigate the clinical effect of methylprednisolone combined with batroxobin in the treatment of sudden deafness and its influence on hemorheology.Methods Sixty two patients with sudden deafness admitted to our hospital from June 2020-December 2023 were randomly divided into control group and test group,with 31 patients in each group.The control group was treated with methylprednisolone,and the test group was treated with batroxobin on the basis of the control group.The hemorheology indexes,therapeutic effectiveness and adverse reactions of the two groups were compared.Results Before treatment,there was no significant difference in hemorheology between the two groups(P>0.05);After treatment,the plasma viscosity and erythrocyte sedimentation rate in the test group were lower than those in the control group(P<0.05).The total effective rate of patients in the test group was 96.77%higher than that in the control group(74.19%,P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The treatment of paroxysmal deafness patients with geolmethylprednisolone combined with batroxobin can improve the hemorheology indexes,improve the treatment effect,and has high safety.
作者
杨中纯
曾瑞芳
Yang Zhongchun;Zeng Ruifang(Changsha Central Hospital(Changsha Central Hospital Affiliated to University of South China),Changsha 410000,China)
出处
《中国医学文摘（耳鼻咽喉科学）》
2024年第5期146-148,共3页
Chinese Medical Digest(Otorhinolaryngology)
基金
湖南省卫生健康委科研计划项目(项目编号:20201960)
长沙市科技计划项目(项目编号:kq2014026)。
关键词
甲泼尼龙
巴曲酶
突发性耳聋
血液流变学指标
治疗有效性
Methylprednisolone
Batroxobin
Sudden deafness
Hemorheology index
Therapeutic effectiveness
