摘要
目的 探讨腺瘤型肠息肉伴上皮内瘤变不同分级患者的中医体质和证素分布特点并阐述二者之间的关系,为临床研究提供依据。方法 对2019年5月-2022年3月就诊且符合纳入标准的150例患者进行中医体质和证素测定,分别运用χ^(2)检验和Logistic回归分析方法分析二者在不同病理分级中的分布特点及相关性。结果 150例患者高级别上皮内瘤变(HGIN)69例,低级别上皮内瘤变(LGIN)81例。经采集,中医体质主要构成为痰湿质[26.00%(39/150)]、阳虚质[18.67%(28/150)]、湿热质[16.67%(25/150)],中医证素主要构成为湿[24.67%(37/150)]、阳虚[16.67%(25/150)]、气滞[(16.00%(24/150)];二者相关性分析显示,痰湿质与湿、痰呈显著正相关性,阳虚质与寒、阳虚呈显著正相关性,湿热质与火、湿呈显著正相关性。结论HGIN和LGIN患者之间,中医体质和证素分布存在一定差异性,且二者存在相关性。
Objective To explore the distribution characteristics of TCM constitution and syndrome elements in patients with adenoma-tous intestinal polyps with different grades of intraepithelial neoplasia,and elaborate the relationship between them,so as to provide basis for clinical research.Methods A total of 150 patients who met the inclusion criteria from May 2019 to March 2022 were tested for TCM constitution and syndrome elements.Chi square test and Logistic regression analysis were used to analyze the distribution characteristics of TCM constitution and syndrome elements in different pathological grades and the correlation between them.Results There were 81 cases of high grade intraepithelial neoplasia(HGIN)and 69 cases of low grade intraepithelial neoplasia(LGIN)in 150 patients.According to the collection of TCM constitution and syndrome elements,TCM constitution mainly consists of phlegm damp-ness(26.00%,39/150),yang deficiency(18.67%,28/150)and damp heat(16.67%,25/150).TCM syndrome elements are mainly com-posed of dampness(24.67%,37/150),yang deficiency(16.67%,25/150)and qi stagnation(16.00%24/150).The correlation analysis between TCM constitution and syndrome elements showed that the phlegm dampness quality was positively correlated with dampness and phlegm.Yang deficiency is positively correlated with cold and yang deficiency.There is a significant positive correlation between damp heat quality and fire and humidity.Conclusion There are some differences between HGIN and LGIN patients in the distribution of TCM constitution and syndrome elements,and there is correlation between TCM constitution and syndrome elements.
作者
李炜
LI Wei(Department of Traditional Chinese Medicine,Shandong College of Traditional Chinese Medicine,Shandong Province,Yantai 264100,China)
出处
《中国中医药现代远程教育》
2024年第22期122-125,共4页
Chinese Medicine Modern Distance Education of China
基金
山东省中医药科技发展计划项目【No.2019-0275】。
关键词
结直肠息肉
上皮内瘤变
中医体质学
证素
卡方检验
Logistic回归分析
colorectal polyps
intraepithelial neoplasia
traditional Chinese medicine constitution
syndrome elements
Chi square test
Logistic regression analysis
