摘要
生殖支原体是近年来新兴的性传播感染病原体,它具有独特的致病机制及隐匿的临床症状,是男、女性泌尿生殖道感染的重要致病微生物。生殖支原体与男性尿道炎、女性宫颈炎、盆腔炎性疾病密切相关,还可能导致输卵管因素不孕症及不良妊娠结局,此外,其与下生殖道感染性疾病(如人乳头瘤病毒感染、细菌性阴道病等)的获得及持续之间存在的关系也被逐步揭示。同时,它对抗生素耐药性的上升也是目前面临的主要挑战。本文就近年来生殖支原体的流行病学、致病机制及相关的女性生殖系统疾病的研究进展作一综述,旨在提高临床工作者对生殖支原体的认识及重视,为防治生殖支原体相关女性生殖系统疾病提供参考。
Mycoplasma genitalium is an emerging sexually transmitted infection pathogen in recent years.It features with a unique pathogenic mechanism and mild symptoms,and is shown to be an important pathogenic microorganism of male and female urogenital tract infections.Mycoplasma genitalium is closely related to male urethritis,female cervicitis and pelvic inflammatory diseases,and could also lead to tubal infertility and adverse pregnancy outcomes.Furthermore,it can also play a crucial role in the acquisition and persistence of lower reproductive tract infectious diseases,such as human papillomavirus infection and bacterial vaginosis.The rise of antibiotic resistance is also a significant challenge.This article reviews the recent research progress on the epidemiology,pathogenic mechanism and related female reproductive system diseases of Mycoplasma genitalium,aiming to enhance the awareness and attention towards Mycoplasma genitalium,thereby providing useful references for prevention and treatment of its related female reproductive system diseases.
作者
赵晓雯
刘朝晖
ZHAO Xiaowen;LIU Zhaohui(Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing Maternal andChild Health Care Hospital.Beijing 100026,China)
出处
《标记免疫分析与临床》
CAS
2024年第9期1717-1722,共6页
Labeled Immunoassays and Clinical Medicine
基金
国家自然科学基金面上项目(编号:81771530)。
关键词
生殖支原体
性传播感染
盆腔炎性疾病
黏液脓性宫颈炎
人乳头瘤病毒
Mycoplasma genitalium
Sexually transmitted infection
Pelvic inflammatory diseases
Mucopurulent cervicitis
Human papillomavirus
