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多节段颈椎前路椎间盘切除融合术后邻近节段退变的危险因素分析

Risk factors analysis of adjacent segment degeneration after multi-segment anterior cervical discectomy and fusion
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摘要 目的探讨多节段颈椎前路椎间盘切除融合术后邻近节段退变的危险因素。方法将213例行多节段颈椎前路椎间盘切除融合术的颈椎病患者根据术后是否发生邻近节段退变分为退变组(40例)与非退变组(173例)。采用logistic回归分析筛选邻近节段退变的危险因素。结果患者均获得随访,时间12~50个月。多因素logistic回归分析显示:邻近节段退变发生的独立危险因素为术前邻近椎间盘退变、术前终板损伤、融合节段数、T 1倾斜角及枕颈角(P<0.05)。结论多节段颈椎前路椎间盘切除融合术后邻近节段退变的发生与融合节段数、术前邻近椎间盘退变程度及颈椎矢状位参数相关。 Objective To investigate the risk factors of adjacent segment degeneration(ASD)after multi-segment anterior cervical discectomy and fusion(ACDF).Methods The 213 patients who were performed with multi-segment ACDF were divided into degeneration group(40 cases)and non-degeneration group(173 cases)based on whether ASD occurred after the surgery.Logistic regression analysis was used to screen for risk factors of ASD.Results All patients were followed up for 12~50 months.Multivariate logistic regression analysis showed that the independent risk factors for ASD were preoperative adjacent disc degeneration,preoperative endplate injury,fusion segment number,T_(1) slope and the occipitocervical angle(P<0.05).Conclusions The occurrence of ASD after multi-segment ACDF is related to the number of fusion segment,preoperative degeneration degree of adjacent disc,and the sagittal parameters of the cervical spine.
作者 范佳俊 陈烽 高威 陈哲 FAN Jia-jun;CHEN Feng;GAO Wei;CHEN Zhe(Dept of Orthopaedics,the Second Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou,Zhejiang 310005,China)
出处 《临床骨科杂志》 2024年第5期609-612,共4页 Journal of Clinical Orthopaedics
基金 国家自然科学基金项目(编号:81873128)。
关键词 颈椎病 颈椎前路椎间盘切除融合术 邻近节段退变 cervical spondylosis anterior cervical discectomy and fusion adjacent segment degeneration
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