摘要
老年人的身体弹性(PR)是指老年人暴露在不良应激源后机体的抵抗或恢复能力,可反映其身体储备能力,是当前老年医学领域的研究热点。不同个体的PR水平存在较大差异,高PR者面对应激源打击时可产生理想的防御或恢复结局,有更低的失能、住院和全因死亡风险,从而获得更长的寿命。目前,影响PR水平的机制尚未明确。因此,本文通过在“Pubmed”数据库中以关键词“Physical Resilience”进行检索,对PR的评估工具、生理机制、影响因素以及血清标志物等方面进行阐述,以期帮助临床更加了解PR,促进健康老龄化。
Physical resilience(PR)in the elderly refers to the physical ability to resist or recover after exposure to adverse stressors,reflecting the body′s reserve capacity.It is currently a much sought topic in geriatrics.PR levels vary greatly among individuals,and high-level individuals have ideal defense or recovery outcomes when exposed to stressors,which leads to lower risks of disability,shorter hospitalization and lower all-cause mortality,and thereby longer lifespan.At present,the mechanisms affecting PR levels remain unclear.Therefore,this article elaborates on the evaluation tools,physiological mechanisms,influencing factors,and serum markers of PR by searching for the keyword"Physical Resilience"in the"Pubmed"database,in order to help clinicians better understand PR and enhance healthy aging.
作者
·综述·芮冬
赵力博
刘霖
Rui Dong;Zhao Libo;Liu Lin(Graduate School,Chinese PLA General Hospital,Beijing 100853,China;Department of Respiratory and Critical Care Medicine,Second Medical Center,Chinese PLA General Hospital,Beijing 100853,China;Department of Cardiology,Second Medical Center,Chinese PLA General Hospital,Beijing 100853,China;National Clinical Research Center for Geriatric Diseases,Chinese PLA General Hospital,Beijing 100853,China)
出处
《中华老年多器官疾病杂志》
2024年第9期713-716,共4页
Chinese Journal of Multiple Organ Diseases in the Elderly
基金
军队保健专项科研课题(22BJZ52,23BJZ27)
军队装备建设应用研究项目(LB20211A010013)
军队实验动物专项研究项目(SYDW_KY[2021]04)。
关键词
老年人
身体弹性
虚弱
应激源
影响因素
aged
physical resilience
frailty
stressor
influencing factor
