摘要
目的探讨临床在超声实时引导下,注射聚桂醇联合无水乙醇硬化治疗老年甲状腺囊肿的疗效。方法选取2021年10月—2023年12月河南省职工医院收治的老年甲状腺囊肿患者94例,随机分成观察组(n=47,超声介入注射聚桂醇联合无水乙醇)和对照组(n=47,超声介入注射无水乙醇),观察治疗总有效率、术中不良反应、术后并发症及术后复发等指标。结果观察组总有效率为93.62%,明显高于对照组(72.34%),差异有统计学意义(P<0.05);两组治疗后1个月、3个月、6个月、12个月的囊肿体积均呈显著下降的趋势且均显著减小;两组术后并发症发生率对比,差异无统计学意义(P>0.05);观察组术中总不良反应发生率为8.51%,明显低于对照组(27.66%),差异有统计学意义(P<0.05);随访期间观察组复发率为2.12%(1/47),对照组复发率为6.38%(3/47)。结论临床硬化治疗老年甲状腺囊肿在超声实时引导下注射聚桂醇联合无水乙醇的疗效评估和安全性较高,患者易于接受,值得临床推广应用。
Objective To explore the therapeutic effect of clinical sclerotherapy for elderly thyroid cysts by real-time ultrasound-guided injection of cinnamyl alcohol combined with anhydrous ethanol.Methods The 94 elderly patients with thyroid cysts admitted to Henan General Hospital from October 2021 to December 2023 were randomly divided into an observation group(n=47,ultrasound-guided injection of lauromacrogol combined with anhydrous ethanol)and a control group(n=47,ultrasound-guided injection of anhydrous ethanol).The total effective rate of treatment,adverse reactions during surgery,postoperative complications and postoperative recurrence were observed and analyed between the two groups.Results The observation group with total effective rate of 93.62%,apparently higher than that of the control group(72.34%),and the difference was statistically significant(P<0.05);after 1,3,6 and 12 months of treatment,the volumes of cysts in both groups showed a significant downward trend and decreased significantly;no statistically significant differences in postoperative complications between the two groups(P>0.05).The total incidence of adverse reactions during surgery in the observation group was 8.51%,apparently lower than that of the control group(27.66%),and the difference was statistically significant(P<0.05);during the follow-up period,the recurrence rate in the observation group was 2.12%(1/47),while the recurrence rate in the control group was 6.38%(3/47).Conclusion For the treatment of elderly thyroid cysts,the efficacy and safety of real-time ultrasound-guided lauromacrogol combined with anhydrous ethanol sclerotherapy are relatively high,easy for patients to accept,and worthy of clinical promotion and application.
作者
杨仁光
高栓杰
朱素芹
寇丽娜
YANG Ren-guang;GAO Shuan-jie;ZHU Su-qin;KOU Li-na(Department of Ultrasound,Henan General Hospital,Zhengzhou 450002,China)
出处
《医药论坛杂志》
2024年第18期2008-2011,F0003,共5页
Journal of Medical Forum
基金
河南省二〇二三年科技发展计划项目(232102310165)。
关键词
超声引导
聚桂醇
老年甲状腺囊肿
硬化治疗
细针穿刺活检
Ultrasound guidance
Lauromacrogol
Elderly thyroid ccysts
Sclerotherapy
Fine-needle aspiration biopsy
