摘要
目的分析1562例绝经后女性人群骨密度与握力之间的相关性。方法收集2022年5月~2023年8月于解放军总医院第一医学中心放射诊断科行骨密度检查与握力测试的1562例绝经后女性人群的骨密度检查结果与握力测试数据。按照年龄分成3组,分别是A组(<60岁,n=663)、B组(60~74岁,n=749)、C组(≥75岁,n=150)。对1562例绝经后女性进行腰椎与股骨近端骨密度检查及优势侧手握力测试。比较3组的骨密度和握力,分析骨密度与握力之间的相关性。结果腰椎骨密度T≤-2.5 SD的患者501例(32.07%);股骨颈骨密度T≤-2.5 SD的患者383例(24.52%);髋部骨密度T≤-2.5 SD的患者186例(11.91%)。A组患者的握力为(22.35±4.64)kg,B组患者的握力为(19.81±4.94)kg,C组患者的握力为(16.57±4.27)kg。握力、骨密度均随着年龄的增长逐渐降低(P<0.05)。共125例患者既往发生过骨折(8.00%),其中A组28例(4.22%),B组66例(8.81%),C组31例(20.67%)。随着患者年龄的增长,骨折的发生率升高(P<0.05)。相关性分析结果显示,绝经后女性人群的握力与股骨颈、髋部、腰椎骨的骨密度均呈正相关(r=0.936、0.938、0.935,P<0.05);握力、股骨颈骨密度、髋部骨密度、腰椎骨密度均与年龄呈负相关(r=-0.928、-0.967、-0.971、-0.970,P<0.05)。握力与腰椎、股骨颈、髋部骨密度均呈正相关(r=0.935、0.936、0.938,P<0.05);握力、股骨颈骨密度、髋部骨密度、腰椎骨密度均与BMI呈正相关(r=0.932、0.982、0.985、0.982,P<0.05)。结论绝经后女性人群的握力与骨密度相互依存,相互影响,呈正相关;握力、骨密度与绝经后女性人群的年龄呈负相关。
Objective To analyze the correlation between bone mineral density(BMD)and grip strength in a cohort of 1,562 postmenopausal women.Methods We collected BMD examination results and grip strength test data from 1,562 postmenopausal women who underwent these tests at the Department of Radiology,First Medical Center of Chinese PLA General Hospital,between May 2022 and August 2023.Patients were divided into three age groups:<60 years(n=663),60-74 years(n=749),and≥75 years(n=150).BMD of the lumbar spine and proximal femur,as well as dominant-side grip strength,were assessed.The BMD and grip strength of the three groups were compared,and the correlation between BMD and grip strength was analyzed.Results Among the patients,501(32.07%)had lumbar spine BMD T-scores≤-2.5;383(24.52%)had femoral neck BMD T-scores≤-2.5;and 186(11.91%)had hip BMD T-scores≤-2.5.Grip strength was(22.35±4.64)kg for the<60 years group,(19.81±4.94)kg for the 60-74 years group,and(16.57±4.27)kg for the≥75 years group.Both grip strength and BMD decreased with increasing age(P<0.05).A total of 125 patients(8.00%)had a history of fractures,with 28(4.22%)in the<60 years group,66(8.81%)in the 60-74 years group,and 31(20.67%)in the≥75 years group.The incidence of fractures increased with age(P<0.05).Correlation analysis showed that grip strength in postmenopausal women was positively correlated with femoral neck,hip,and lumbar spine BMD(r=0.145,0.139,0.107,respectively;P<0.05).Grip strength,femoral neck BMD,hip BMD,and lumbar spine BMD were all negatively correlated with age(r=0.230,-0.395,-0.378,-0.259,respectively;P<0.05).Grip strength was positively correlated with lumbar spine,femoral neck,and hip BMD(r=0.935,0.936,0.938,respectively;P<0.05).Grip strength,femoral neck BMD,hip BMD,and lumbar spine BMD were all positively correlated with BMI(r=0.032,0.265,0.321,0.283,respectively;P<0.05).Conclusion Grip strength and BMD are interdependent and positively correlated in postmenopausal women,while both are negatively correlated with age.
作者
高登发
张晓晶
齐叶青
李萌
官剑武
贾红
Gao Dengfa;Zhang Xiaojing;Qi Yeqing(Department of Radiology,First Medical Center,Chinese PLA General Hospital,Beijing 100853,China)
出处
《中华保健医学杂志》
2024年第5期659-661,共3页
Chinese Journal of Health Care and Medicine
关键词
骨密度
握力
绝经后
正相关
负相关
Bone mineral density
Grip strength
Postmenopausal
Positive correlation
Negative correlation
