摘要
目的探讨在急诊阵发性室上性心动过速(paroxysmal supraventricular tachycardia,PSVT)患者中应用盐酸胺碘酮注射液结合盐酸普罗帕酮注射液治疗的具体影响。方法回顾性选取淄博昌国医院于2020年4月—2023年8月收治的80例急诊PSVT患者的临床资料,按照治疗方法将患者分为观察组、对照组。对照组(40例)皮下注射盐酸普罗帕酮注射液,观察组(40例)在对照组基础上皮下注射盐酸胺碘酮注射液。比较两组的临床疗效、血压水平、心功能指标、不良反应发生情况。结果观察组治疗总有效率为92.50%(37/40),高于对照组的75.00%(30/40),差异有统计学意义(χ^(2)=4.501,P<0.05);治疗后观察组收缩压、左室收缩末期容积、舒张压、左室舒张末期内径、左室舒张末期容积均较对照组低,左心室射血分数较对照组高,差异有统计学意义(P均<0.05);两组的不良反应发生情况比较,差异无统计学意义(P>0.05)。结论盐酸胺碘酮注射液结合盐酸普罗帕酮注射液用于PSVT患者,具有明显治疗效果,可对患者血压进行有效调节,改善心功能水平,且用药安全性高。
Objective To explore the specific effects of amiodarone hydrochloride injection combined with propafenone hydrochloride injection on emergency paroxysmal supraventricular tachycardia(PSVT)patients.Methods Clinical data of eighty patients with emergency PSVT admitted to Changguo Hospital of Zibo from April 2020 to August 2023 were retrospectively selected,and the patients were divided into observation group and control group according to treatment methods.The control group(forty cases)received subcutaneous injection of propafenone hydrochloride,and the observation group(forty cases)received subcutaneous injection of amiodarone hydrochloride under the basal epithelium of the control group.The clinical efficacy,blood pressure level,cardiac function index and the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 92.50%(37/40),which was higher than 75.00%(30/40)of the control group,the difference was statistically significant(χ^(2)=4.501,P<0.05).After treatment,systolic blood pressure,left ventricular end-systolic volume,diastolic blood pressure,left ventricular end-diastolic diameter and left ventricular end-diastolic volume in observation group were lower than those in control group,and left ventricular ejection fraction was higher than that in control group,the differences were statistically significant(all P<0.05).There was no statistically significant difference in the occurrence of adverse reactions between the two groups(P>0.05).Conclusion Amiodarone hydrochloride injection combined with propafenone hydrochloride injection for PSVT patients has obvious therapeutic effect,can effectively regulate the blood pressure of patients,improve the level of cardiac function,and the drug safety is high.
作者
张宇明
ZHANG Yuming(Emergency Medicine Department,Changguo Hospital in Zibo,Zibo 255000,Shandong,China)
出处
《系统医学》
2024年第18期47-50,共4页
Systems Medicine
关键词
阵发性室上性心动过速
胺碘酮
普罗帕酮
血压
心功能指标
Paroxysmal supraventricular tachycardia
Amiodarone
Propafenone
Blood pressure
Cardiac function indicators
