摘要
目的分析腰大肌指数(psoas major index,PMI)对弥漫大B细胞淋巴瘤(diffuse large B-cell lymphoma,DLBCL)患者营养风险的预测价值。方法回顾分析西安交通大学第一附属医院血液内科2021年1月1日到2024年3月1日DLBCL收治入院的患者100例。调取患者腹部影像资料,计算患者PMI。调取营养风险筛查相关资料,将患者依据营养风险筛查量表(NRS 2002)分为营养风险组和非营养风险组,比较两组患者间一般资料及PMI的差异,使用多因素二元Logistic回归分析DLBCL患者发生营养风险的影响因素,采用ROC曲线分析PMI对DLBCL患者营养风险的预测价值。结果营养风险组和非营养风险组间有无B症状(发热、盗汗、体重下降)、细胞起源、国际预后指数(IPI)评分、乳酸脱氢酶(LDH)、淋巴细胞计数(LY)、身体质量指数(BMI)、PMI均存在统计学差异(P<0.05),细胞起源、IPI评分、BMI、PMI为DLBCL患者发生营养风险的影响因素,PMI、BMI、IPI评分、LDH、LY预测DLBCL患者营养风险发生的AUC分别为0.794、0.756、0.684、0.675、0.650。结论PMI为DLBCL患者营养风险发生的影响因素,PMI对DLBCL患者营养风险评估具有一定价值。
Objective To analyze the predictive value of psoas major index(PMI)of nutritional risk in patients with diffuse large B-cell lymphoma(DLBCL).Methods A retrospective analysis was conducted on 100 patients with DLBCL admitted to the department of hematology,the First Affiliated Hospital of Xi’an Jiaotong University,from January 1,2021,to March 1,2024.Abdominal imaging data were obtained to calculate the PMI for each patient.Relevant data on nutritional risk screening were collected,and patients were divided into a nutritional risk group and a non-nutritional risk group based on the Nutritional Risk Screening Scale 2002(NRS 2002).Differences in general information and PMI were compared between the two groups.Multivariate binary Logistic regression analysis was used to analyze the factors influencing the occurrence of nutritional risk in DLBCL patients.The ROC curve was employed to analyze the predictive value of PMI for nutritional risk in DLBCL patients.Results Statistically significant differences were observed between the nutritional risk group and the non-nutritional risk group in terms of B symptoms(fever,night sweats,weight loss),cell origin,International Prognostic Index(IPI)score,lactate dehydrogenase(LDH)level,lymphocyte count(LY),body mass index(BMI),and PMI(P<0.05).Cell origin,IPI score,BMI,and PMI were identified as factors influencing the occurrence of nutritional risk in DLBCL patients.The AUCs for predicting nutritional risk in DLBCL patients were 0.794 for PMI,0.756 for BMI,0.684 for IPI score,0.675 for LDH,and 0.650 for LY.Conclusion PMI is a factor influencing the occurrence of nutritional risk in DLBCL patients,and it has certain value in assessing nutritional risk in this patient population.
作者
朱玉珍
张宇宏
王晓宁
王崇祥
贺鹏程
ZHU Yuzhen;ZHANG Yuhong;WANG Xiaoning;WANG Chongxiang;HE Pengcheng(Department of Hematology,The First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710061,Shanxi,China;Xi’an International Medical Center Hospital,Xi’an 710117,Shanxi,China;Department of Pain Treatment,The First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710061,Shanxi,China)
出处
《右江民族医学院学报》
2024年第5期671-675,共5页
Journal of Youjiang Medical University for Nationalities
基金
陕西省重点研发计划(2022SF-013)。
关键词
营养风险
腰大肌指数
弥漫大B细胞淋巴瘤
nutritional risk
psoas major muscle index
diffuse large B-cell tumor
