期刊文献+

替罗非班诱导血小板减少症的研究进展

Advances in Tirofiban-induced Thrombocytopenia
下载PDF
导出
摘要 替罗非班诱导血小板减少症(tirofiban-induced thrombocytopenia,TIT)通常被认为是一种由药物引发的免疫性血小板减少症,表现为使用替罗非班后血小板快速大幅度减少。随着替罗非班在心脑血管领域的广泛应用,TIT病例报道随之增多,受到医学界关注。本文综述了TIT的研究进展,概述了其临床表现、发病机制、危险因素、诊断及鉴别诊断,并讨论了治疗策略,旨在为临床医生提供更全面的诊治参考,以期优化TIT的管理。 Tirofiban-induced thrombocytopenia(TIT)is a drug-induced immune thrombocytopenia that manifests itself as a significant reduction in platelets after the use of tirofiban.With the increasing use of tirofiban in the cardio-cerebrovascular field,the number of TIT cases is increasing and has received attention from the medical community.This article reviews the research progress of TIT,outlines its clinical manifestations,mechanisms,risk factors,diagnostic methods and differential diagnosis,and focuses on therapeutic strategies.The aim of this article is to provide clinicians with a more comprehensive diagnosis and treatment reference with a view to optimizing the management of TIT.
作者 付娜娜 李文文 FU Nana;LI Wenwen(Department of Neurology,Juye County People's Hospital,Heze,Shandong,274900,China)
出处 《中外医疗》 2024年第27期196-198,共3页 China & Foreign Medical Treatment
关键词 替罗非班 血小板减少症 免疫性 Tirofiban Thrombocytopenia Immunity
  • 相关文献

参考文献9

二级参考文献47

  • 1Yuan-Lin Guo , Jian-Jun Li , Jin-Qing Yuan , Xue-Wen Qin , Xin Zheng , Chao-Wei Mu , Yi-Hong Hua.Profound thrombocytopenia induced by clopidogrel with a prior history of long-term safe administration[J].World Journal of Cardiology,2010,2(6):160-162. 被引量:9
  • 2李月平,周玉杰,刘宇扬,张妍,梁静.经皮冠状动脉介入治疗术后替罗非班诱发极重度血小板减少症二例[J].中国介入心脏病学杂志,2006,14(5):315-315. 被引量:14
  • 3Valgimigli M, Tebaldi M. Safety evaluation of tirofiban[J].Expert Opin Drug Saf,2010,9(5) : 801-819.
  • 4The RESTORE Investigators. Effects of platelet glycoproteinII b/ IE a blockade with tirofiban on adverse cardiac events inpatients with unstable angina or acute myocardial infarctionundergoing coronary angioplasty [ J]. Circulation, 1997,96(5): 1445-1453.
  • 5Weitz J. Antithrombotic drugs[M]// Hoffman R and ShattilS. Hematology basic principles and practice. 5th ed.Philadelphia: Elsevier. 2009 : 2070.
  • 6Dasgupta H, Blankenship JC, Wood GC, et al.Thrombocytopenia complicating treatment with intravenousglycoprotein Ilb/IIIa receptor inhibitors: a pooled analysis[J].Am Heart J,2000, 140(2): 206-211.
  • 7Huxtable LM, Tafreshi MJ, Rakkar AN. Frequency andmanagement of thrombocytopenia with the glycoprotein lib/Ilia receptor antagonists[J]. Am J Cardiol,2006 , 97(3) : 426-429.
  • 8Balamuthusamy S,Arora R. Hematologic adverse effects ofclopidogrel[J]. Am J Ther,2007,14(1) : 106-112.
  • 9Mangalpally KK, Kleiman NS. The safety of clopidogrel[J].Expert Opin Drug Saf, 2011,10(1) : 85-95.
  • 10Bougie DW, Wilker PR, Wuitschick . ED, et al. Acutethrombocytopenia after treatment with tirofiban or eptifibatideis associated with antibodies specific for ligand-occupiedGPIIb/IIIa[J]. Blood, 2002,100(6): 2071-2076.

共引文献33

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部